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Probiotic prophylaxis in patients with predicted severe acute pancreatitis (PROPATRIA): design and rationale of a double-blind, placebo-controlled randomised multicenter trial [ISRCTN38327949]

Marc GH Besselink*, Harro M Timmerman, Erik Buskens, Vincent B Nieuwenhuijs, Louis MA Akkermans, Hein G Gooszen and the members of the Dutch Acute Pancreatitis Study Group

BMC Surgery 2004, 4:12  doi:10.1186/1471-2482-4-12