Open Access Highly Accessed Case report

Non-operative treatment for perforated gastro-duodenal peptic ulcer in Duchenne Muscular Dystrophy: a case report

Justus-Martijn Brinkman1, Jorg R Oddens2, Barend J Van Royen1*, Jan Wever2 and Jan G Olsman2

Author Affiliations

1 Department of Orthopaedics, VU medical centre, Amsterdam, The Netherlands Address: De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands

2 Department of Surgery, Jeroen Bosch Hospital, Den Bosch, The Netherlands Address: Tolbrugstraat 11, 5211 RW Den Bosch, The Netherlands

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BMC Surgery 2004, 4:1  doi:10.1186/1471-2482-4-1

Published: 8 January 2004



Clinical characteristics and complications of Duchenne muscular dystrophy caused by skeletal and cardiac muscle degeneration are well known. Gastro-intestinal involvement has also been recognised in these patients. However an acute perforated gastro-duodenal peptic ulcer has not been documented up to now.

Case presentation

A 26-year-old male with Duchenne muscular dystrophy with a clinical and radiographic diagnosis of acute perforated gastro-duodenal peptic ulcer is treated non-operatively with naso-gastric suction and intravenous medication. Gastrointestinal involvement in Duchenne muscular dystrophy and therapeutic considerations in a high risk patient are discussed.


Non-surgical treatment for perforated gastro-duodenal peptic ulcer should be considered in high risk patients, as is the case in patients with Duchenne muscular dystrophy. Patients must be carefully observed and operated on if non-operative treatment is unsuccessful.