Table 5

The 10 Most Frequent AEs (Safety Population)


Lumiracoxib 100 mg o.d. (n = 755)
Lumiracoxib 100 mg b.i.d. (n = 1,519)
Celecoxib 200 mg o.d. (n = 758)

Headache
82 (10.9)
174 (11.5)
82 (10.8)
Nasopharyngitis
80 (10.6)
141 (9.3)
75 (9.9)
Back pain
46 (6.1)
87 (5.7)
52 (6.9)
Arthralgia
53 (7.0)
82 (5.4)
41 (5.4)
Abdominal pain upper
42 (5.6)
88 (5.8)
35 (4.6)
Upper respiratory tract infection
36 (4.8)
86 (5.7)
43 (5.7)
Dyspepsia
38 (5.0)
85 (5.6)
39 (5.1)
Urinary tract infection
38 (5.0)
75 (4.9)
24 (3.2)
Sinusitis
21 (2.8)
58 (3.8)
34 (4.5)
Influenza
30 (4.0)
53 (3.5)
28 (3.7)

o.d. = once daily; b.i.d. = twice daily.

Fleischmann et al. BMC Musculoskeletal Disorders 2008 9:32   doi:10.1186/1471-2474-9-32