Table 2

Treatment Comparisons of the Retention Rate at 1 Year (ITT Population)

Treatment group
N
Retention rate, n (%)
Contrasts
Estimated difference (97.5% CI)
Outcome

Lumiracoxib 100 mg
755
354 (46.9)
Lumiracoxib 100 mg o.d.
0.02 (-0.04, 0.07)
Non-inferior
o.d.


- celecoxib 200 mg o.d.


Lumiracoxib 100 mg
1519
722 (47.5)
Lumiracoxib 100 mg b.i.d.
0.02 (-0.03, 0.07)
Non-inferior
b.i.d.


- celecoxib 200 mg o.d.


Celecoxib 200 mg
758
343 (45.3)



o.d.






CI = confidence interval; o.d. = once daily; b.i.d. = twice daily; ITT = intention-to-treat.

Fleischmann et al. BMC Musculoskeletal Disorders 2008 9:32   doi:10.1186/1471-2474-9-32