Table 1

Baseline Patient Characteristics (ITT Population)


Lumiracoxib 100 mg o.d. (n = 755)
Lumiracoxib 100 mg b.i.d. (n = 1,519)
Celecoxib 200 mg o.d. (n = 758)

Age (years), mean ± SD
62.9 ± 10.25
62.2 ± 10.02
62.7 ± 10.00
Females, n (%)
541 (71.7)
1081 (71.2)
531 (70.1)
BMI (kg/m2), mean ± SD
29.5 ± 6.41
29.7 ± 6.34
29.8 ± 6.33
Race, n (%)



     White/Caucasian
712 (94.3)
1450 (95.5)
731 (96.4)
     Black/African American
22 (2.9)
45 (3.0)
13 (1.7)
     Hispanic
10 (1.3)
8 (0.5)
11 (1.5)
     Other
11 (1.5)
16 (1.1)
3 (0.4)
Disease duration (years), mean ± SD
7.9 ± 7.73
7.6 ± 7.79
7.5 ± 7.62
Target joint, n (%)



     Hip
58 (7.7)
122 (8.0)
59 (7.8)
     Knee
376 (49.8)
743 (48.9)
350 (46.2)
     Hand
159 (21.1)
301 (19.8)
166 (21.9)
     Spine
162 (21.5)
353 (23.2)
183 (24.1)
OA pain, n (%)



     Mild
48 (6.4)
102 (6.7)
49 (6.5)
     Moderate
363 (48.1)
704 (46.3)
346 (45.6)
     Severe
343 (45.4)
712 (46.9)
361 (47.6)
     Extreme
1 (0.1)
1 (0.1)
2 (0.3)
Patient's global assessment of disease activity, n (%)



     Very good
2 (0.3)
8 (0.5)
4 (0.5)
     Good
94 (12.5)
167 (11.0)
78 (10.3)
     Fair
340 (45.0)
711 (46.8)
360 (47.5)
     Poor
296 (39.2)
581 (38.2)
287 (37.9)
     Very poor
23 (3.0)
51 (3.4)
29 (3.8)
Physician's global assessment of disease activity, n (%)



     Very good
1 (0.1)
0 (0.0)
2 (0.3)
     Good
51 (6.8)
85 (5.6)
45 (5.9)
     Fair
371 (49.1)
784 (51.6)
373 (49.2)
     Poor
317 (42.0)
618 (40.7)
324 (42.7)
     Very poor
14 (1.9)
31 (2.0)
12 (1.6)
Short Arthritis assessment Scale (SAS) total score, mean ± SD
22.4 ± 7.81
22.1 ± 7.61
22.3 ± 7.86

o.d. = once daily; b.i.d. = twice daily; BMI = body mass index; ITT = intention-to-treat; SD = standard deviation; Japanese, other Asian or Pacific Islander or other.

Fleischmann et al. BMC Musculoskeletal Disorders 2008 9:32   doi:10.1186/1471-2474-9-32