|
Baseline demographic and clinical characteristics of treatment groups |
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| Topical diclofenac (n = 107) |
Vehicle control (n = 109) |
|
|
|
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| Age (years) |
65.0 (11.0) |
64.6 (10.9) |
| Women, number (%) |
56 (52.3) |
66 (60.6) |
| Race/ethnicity, number (%) |
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| White |
88 (82.2) |
91 (83.5) |
| Black |
8 (7.5) |
3 (2.8) |
| Oriental |
3 (2.8) |
2 (1.8) |
| Other |
8 (7.5) |
13 (11.9) |
| Weight (kg) |
89.9 (18.1) |
86.5 (17.3) |
| Height (m) |
1.65 (0.11) |
1.65 (0.10) |
| Heart rate (bpm) |
74.1 (10.0) |
74.3 (9.1) |
| Systolic blood pressure (mm Hg) |
137.6 (16.3) |
133.6 (15.6) |
| Diastolic blood pressure (mm Hg) |
81.4 (9.1) |
79.7 (8.7) |
| Total x-ray score* |
7.7 (5.4) |
7.0 (5.0) |
| Screening pain score |
8.2 (2.7) |
8.3 (3.0) |
| Baseline† pain score |
13.0 (3.2) |
12.8 (3.1) |
| Baseline† physical function score |
40.7 (11.9) |
40.4 (11.2) |
| Baseline† stiffness score |
5.2 (1.5) |
5.2 (1.5) |
| Patient global assessment score‡ |
3.1 (0.8) |
3.2 (0.8) |
| Participants treating two knees at baseline, number (%) |
64 (59.8) |
70 (64.2) |
| Participants treating two knees at final, number (%) |
84 (78.5) |
89 (81.7) |
|
Data are presented as mean (SD) unless otherwise indicated. *Total score of joint space narrowing, marginal osteophytes formation and subchondrial sclerosis for each knee compartment (medial, lateral, patello-femoral); maximum score possible was 27. †After washout of prior therapy; pain scale ranged from 0 (no pain) to 20 (extreme pain); physical function scale ranged from 0 (no difficulty) to 68 (extreme difficulty); stiffness scale ranged from 0 (no stiffness) to 8 (extreme stiffness). ‡Patient global assessment was measured using a Likert scale, ranging from 0 (very good) to 4 (very poor). | ||
Baer et al. BMC Musculoskeletal Disorders 2005 6:44 doi:10.1186/1471-2474-6-44 |
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