Table 1

List of relevant baseline characteristics
Outcome
Pain Function Structure
General information
Age Age Age
Gender Gender Gender
Activity level in daily life Activity level in daily life
Psychosocial factors
Pain catastrophizing
Anxiety and Fear
Depression Depression
Quality of life* Quality of life*
Information from history
Primary or secondary osteoarthritis
Duration since onset of symptoms indicating knee osteoarthritis Duration since onset of symptoms indicating knee osteoarthritis Duration since onset of symptoms indicating knee osteoarthritis
Intermittent or constant pain Intermittent or constant pain
Pain remained constant or varied in the last week
Average daily pain during the last week Average daily pain during the last week
Walking aid needed (e.g., cane/walker)
Global knee pain** Global knee pain** Global knee pain**
Waking up with pain
Weight bearing pain Weight bearing pain
Pain at rest
Pain when going down stairs
Function of knee*** Function of knee*** Function of knee***
Pain or reduced function in other joints (hip/spine) Pain or reduced function in other joints (hip/spine)
Previous history of knee trauma
Previous history of meniscal tear or meniscectomy
Previous history of ACL§ rupture
Previous surgical intervention
Daily dose of pain killers (NSAIDs)
Information from physical examination
BMI BMI BMI
Physical functional ability; e.g., performance tests of baseline physical ability (e.g., the Timed Up and Go test or a 6-min walking test)
Lab results
Imaging results
Kellgren-Lawrence grading (weight bearing)
Bone marrow lesions
Joint space width
Synovitis (US§§, MRI§§§)
Effusion (US, MRI)
Involved joint compartment (i.e., patellofemoral vs. tibiofemoral vs. combined etc.)
Meniscus tear
Meniscus extrusion
ACL tear
Cartilage abnormalities (MRI)
Malalignment (hip-knee-ankle mechanical axis)
Cartilage volume/thickness in the compartment of interest (MRI)

Legend: List of baseline characteristics with a median rating of importance ≥7 according to three different outcome categories, based on the opinions of an expert panel.

Abbreviations: *e.g., SF-36; **e.g., VAS, WOMAC; ***e.g., WOMAC, Lequesne; § Anterior crucial ligament; §§ Ultrasound; §§§ Magnetic Resonance Imaging.

Wildi et al.

Wildi et al. BMC Musculoskeletal Disorders 2013 14:369   doi:10.1186/1471-2474-14-369

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