Table 2

Unadjusted trabecular bone microarchitecture measures for participants with valid MRI images who completed both baseline and follow-up assessments
Women with type 2 diabetes Controls
Baseline n= 14 Follow-up n= 14 Absolute change from baseline Baseline n= 21 Follow-up n= 21 Absolute change from baseline Between group difference p-value
Hole size, mm2 2.10 (0.47) 2.04 (0.37) −0.06 (0.48) 2.06 (0.42) 2.08 (0.45) 0.03 (0.32) 0.513
Number of holes 68 (17) 69 (13) 1 (15) 72 (15) 68 (18) −4 (12) 0.283
Endosteal area, mm2 260.7 (51.1) 264.8 (56.9) 4.0 (39.9) 273.2 (58.4) 258.3 (48.9) −14.9 (39.6) 0.939
BVTV, % 47.7 (1.0) 47.9 (0.8) 0.2 (0.9) 47.7 (1.2) 47.8 (1.0) 0.1 (0.7) 0.759
Tb.Th, mm 0.52 (0.01) 0.51 (0.01) 0 (0.01) 0.51 (0.01) 0.51 (0.01) 0 (0.01) 0.549
Tb.Sp, mm 0.55 (0.01) 0.54 (0.01) 0 (0.01) 0.54 (0.02) 0.54 (0.02) 0 (0.01) 0.322
Tb.N,/mm 0.92 (0.03) 0.93 (0.02) 0.01 (0.02) 0.93 (0.03) 0.93 (0.03) 0 (0.01) 0.362
Nodal density, /mm2 0.16 (0.01) 0.16 (0.01) 0 (0.01) 0.16 (0.01) 0.15 (0.01) 0 (0.01) 0.574
Branch density, /mm2 0.41 (0.06) 0.42 (0.05) 0.01 (0.05) 0.41 (0.05) 0.42 (0.06) 0.01 (0.05) 0.940

Values are mean (SD). Between group difference for absolute change in trabecular bone microarchitecture measures for women with and without type 2 diabetes.

Abbreviations: BVTV, bone volume fraction; Tb.Th, trabecular thickness; Tb.Sp, trabecular separation; Tb.N, trabecular number.

Pritchard et al.

Pritchard et al. BMC Musculoskeletal Disorders 2013 14:114   doi:10.1186/1471-2474-14-114

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