Table 2

Number of studies reporting on associations between potential risk factors and revision of primary THA
Specific endpoint Revision (any) Aseptic loosening Infection Dislocation
Total for each endpoint* 65 30 19 12
Risk Factor N^ (%)+ N (%) N (%) N (%)
Demographic Factors
Age 26 (40%) 12 (40%) 5 (26%) 4 (33%)
Sex 18 (28%) 10 (33%) 6 (32%) 2 (17%)
BMI/body weight 5 (8%) 2 (7%) 2 (11%) 1 (8%)
Race 1 (2%) 1 (5%)
Socioeconomic status 1 (2%) 1 (5%)
Tobacco use 1 (3%)
Alcohol use 1 (5%)
Preparation of living aids 1 (3%)
Clinical Factors
Underlying diagnosis 21 (32%) 8 (27%) 6 (32%) 3 (25%)
Comorbidity (Charlson) 5 (8%) 2 (11%)
Diabetes 1 (2%) 1 (3%) 2 (11%) 1 (8%)
Medication use 3 (5%) 4 (13%) 3 (16%) 3 (25%)
Bilateral vs. unilateral THA 3 (5%)
Genetic predisposition 1 (3%) 2 (11%)
Prior hip surgery 1 (2%) 1 (3%) 1 (5%)
Post-THA childbirth 1 (2%)
Surgical and Implant-Related Factors
Fixation 11 (17%) 6 (20%) 6 (32%) 2 (17%)
Femoral head size 3 (5%) 2 (7%) 3 (25%)
Bearing 1 (2%) 1 (3%) 1 (8%)
Coating 1 (2%) 1 (3%)
Femoral head material 1 (2%)
Other design-related factors 1 (2%) 2 (7%) 1 (5%)
Operating time 2 (3%) 1 (3%) 4 (21%) 2 (17%)
Surgical approach 1 (2%) 1 (3%) 1 (5%) 3 (25%)
Ventilation 1 (2%) 2 (11%)
Anesthesia 2 (11%)
Infection prophylaxis 1 (2%) 1 (3%) 1 (5%)
Fixation technique 1 (2%) 1 (3%)
Units blood transfused 1 (5%)
Health Care Provider-Related Factors
Hospital volume 6 (9%) 1 (3%)
Hospital teaching status 2 (3%) 1 (5%)
Rural vs. urban hospital 1 (5%)
Surgeon volume 4 (6%)
Surgeon experience 2 (3%)

* Papers that reported on multiple endpoints are included in each of the relevant columns.

^ — indicates no papers examined the risk factor for that endpoint.

+ Column percentages, not mutually exclusive.

Prokopetz et al.

Prokopetz et al. BMC Musculoskeletal Disorders 2012 13:251   doi:10.1186/1471-2474-13-251

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