Table 3

Differently expressed gene ontology between KBD cartilage and healthy cartilage
Gene Ontology Category Function NESa P-value
APOPTOSIS_GO Apoptosis 0.450 0.032
REGULATION_OF_APOPTOSIS Apoptosis 0.470 0.032
REGULATION_OF_PROGRAMMED_CELL_DEATH Apoptosis 0.470 0.032
ANTI_APOPTOSIS Apoptosis 0.551 <0.001
ORGAN_DEVELOPMENT Development 0.511 <0.001
SYSTEM_DEVELOPMENT Development 0.512 <0.001
REGULATION_OF_DEVELOPMENTAL_PROCESS Development 0.473 0.050
ORGAN_MORPHOGENESIS Development 0.663 <0.001
ANATOMICAL_STRUCTURE_DEVELOPMENT Development 0.506 <0.001

a denotes normalized enrichment score (NES) calculated by GSEA. Positive NES indicate gene ontology up-regulated in KBD cartilage compared to healthy cartilage.

Zhang et al.

Zhang et al. BMC Musculoskeletal Disorders 2012 13:130   doi:10.1186/1471-2474-13-130

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