Table 3 |
|||
| Differently expressed gene ontology between KBD cartilage and healthy cartilage | |||
| Gene Ontology Category | Function | NESa | P-value |
| APOPTOSIS_GO | Apoptosis | 0.450 | 0.032 |
| REGULATION_OF_APOPTOSIS | Apoptosis | 0.470 | 0.032 |
| REGULATION_OF_PROGRAMMED_CELL_DEATH | Apoptosis | 0.470 | 0.032 |
| ANTI_APOPTOSIS | Apoptosis | 0.551 | <0.001 |
| ORGAN_DEVELOPMENT | Development | 0.511 | <0.001 |
| SYSTEM_DEVELOPMENT | Development | 0.512 | <0.001 |
| REGULATION_OF_DEVELOPMENTAL_PROCESS | Development | 0.473 | 0.050 |
| ORGAN_MORPHOGENESIS | Development | 0.663 | <0.001 |
| ANATOMICAL_STRUCTURE_DEVELOPMENT | Development | 0.506 | <0.001 |
a denotes normalized enrichment score (NES) calculated by GSEA. Positive NES indicate gene ontology up-regulated in KBD cartilage compared to healthy cartilage.
Zhang et al. BMC Musculoskeletal Disorders 2012 13:130 doi:10.1186/1471-2474-13-130
