Table 5

Prospective impact of directly measured SHS exposure on COPD-related health status at 1 year follow-up (n = 68)

SHS exposure

COPD severity

Physical health status (SF-12)

Disease-specific QOL

Dyspnea

Bivariate

Multivariate

Bivariate

Multivariate

Bivariate

Multivariate

Bivariate

Multivariate

Urine cotinine

1^st tertile

Referent

Referent

Referent

Referent

Referent

Referent

Referent

Referent

2^nd tertile

2.8 (-1.2 to 6.7)

1.9 (-2.3 to 6.0)

0.4 (-6.3 to 7.0)

2.6 (-4.2 to 9.4)

-0.3 (-3.1 to 2.5)

-1.4 (-4.1 to 1.3)

0.1 (-0.8 to 0.6)

-0.2 (-0.8 to 0.4)

3^rd tertile

5.8 (1.5 to 10.2)

4.7 (-0.1 to 9.4)*

-7.8 (-15 to -0.6)

-5.7 (-14 to 2.0)

4.5 (1.3 to 7.6)

2.9 (-0.16 to 5.9)^†

1.2 (0.5 to 1.9)

0.9 (0.2 to 1.6)

Nicotine badge

1^st tertile

Referent

Referent

Referent

Referent

Referent

Referent

Referent

Referent

2^nd tertile

0.5 (-3.6 to 4.6)

1.0 (-3.3 to 5.3)

0.1 (-6.8 to 6.9)

-0.2 (-7.2 to 6.9)

-0.2 (-3.1 to 2.8)

0.3 (-2.5 to 3.0)

-0.1 (-0.8 to 0.6)

0 (-0.7 to 0.6)

3^rd tertile

-0.7 (-4.8 to 3.5)

-0.3 (-4.6 to 4.0)

-1.1 (-8.1 to 5.9)

-2.1 (-9.2 to 5.0)

-0.1 9–3.1 to 2.9)

0.9 (-1.9 to 3.7)

0 (-0.6 to 0.7)

0.2 (-0.5 to 0.8)

All values are mean score change compared to lowest exposure tertile (referent group) and 95% confidence interval. Multivariate analysis controls for age, sex, race, educational attainment, and past smoking history. Physical health status was measured by the SF-12 physical component summary score; Disease-specific QOL was measured by the Airways Questionnaire 20 (AQ-20); Dyspnea was measured by the modified MRC Dyspnea Scale. Higher scores = worse status, except for SF-12 physical score.

Boldface = p < 0.05.

*p = 0.054

^†p = 0.063

Eisner et al. BMC Pulmonary Medicine 2006 6:12   doi:10.1186/1471-2466-6-12