Research article

Evaluation of a portable hemoglobin photometer in pregnant women in a high altitude area: a pilot study

Xiaoyan Zhou¹ , Hong Yan¹ , Yuan Xing¹ , Shaonong Dang¹ , Bianba Zhuoma² and Duolao Wang³

¹  Department of Epidemiology and Health Statistics, Xi'an Jiaotong University College of Medicine, Xi'an, PR China

²  Obstetrics and Gynecology Department, Lhasa People's Hospital, Lhasa, PR China

³  Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, WC1E 7HT, UK

author email corresponding author email

BMC Public Health 2009, 9:228doi:10.1186/1471-2458-9-228

Published:	11 July 2009

Abstract

Background

Anemia is a widespread public health problem associated with an increased risk of morbidity and mortality, especially in pregnant women. This study examined the agreement between a portable hemoglobin photometer and a laboratory analyzer in determining hemoglobin level in pregnant women.

Methods

This study recruited 69 pregnant women in Tibet, China. Capillary blood samples were taken to measure hemoglobin concentration using the hemoglobin photometer and the laboratory analyzer. Limit of agreement, concordance and intraclass correlation coefficient were used to evaluate the agreement. Laboratory measurement was considered as the standard reference method. Sensitivity and specificity were calculated to assess the error in screening for anemia.

Results

Mean difference between the two methods was -2.1 g/l. wide 95% limits of agreement were found (-22.6 g/l to 18.4 g/l). The intraclass correlation coefficient was 0.795, and concordance correlation coefficient was 0.793. Sensitivity and specificity were 94.9% and 76.7% respectively. Positive predictive value was 84.1%, and negative predictive value was 92.0%.

Conclusion

This hemoglobin photometer is not recommended for determining hemoglobin concentration in pregnancy in a high altitude area.