Table 2

Factors associated with dyslipidaemia from a multiple logistic regression model
Variables TC ≥ 200 mg/dl LDL-c ≥ 130 mg/dl TG ≥ 150 mg/dl HDL-c < 40 mg/dl TC/HDL-c ratio ≥5
Adjusted OR (95%CI) Adjusted OR (95%CI) Adjusted OR (95%CI) Adjusted OR (95%CI) Adjusted OR (95%CI)
Sex
Male 1 1 1 1 1
Female 2.11 (0.64-6.95) 0.44 (0.14-1.38) 1.47 (0.53-4.08) 2.55 (0.51-12.64) 3.25 (0.56-18.92)
P-value 0.22 0.16 0.45 0.25 0.19
Age group (years)
15 – 24 1 1 1 1 1
25 – 34 0.91 (0.19-4.28) 1.00 (0.03-31.54) 1.20 (0.27-5.30) 1.47 (0.21-10.40) 1.42 (0.19-10.76)
35+ NA 0.28 (0.01-11.70) NA NA NA
P-value 0.56 0.07 0.81 0.70 0.48
CD4 count
<350 1 1 1 1 1
350 – 499 1.12 (0.30-4.14) 1.30 (0.38-4.48) 1.23 (0.38-3.89) 1.24 (0.27-5.66) 1.23 (0.33-8.33)
500+ 2.45 (0.73-8.26) 0.77 (0.22-2.64) 0.97 (0.33-2.86) 0.57 (0.11-2.76) 1.28 (0.25-6.59)
P-value 0.56 0.07 0.46 0.65 0.48
Time on ART(years)
<2 1 1 1 1 1
2 – 4 2.16 (0.64-7.33) 5.22 (1.43-19.06) 0.51 (0.16-1.59) 1.71 (0.34-8.48) 1.65 (0.33-8.33)
5+ 1.11 (0.33-3.75) 1.59 (0.45-5.57) 0.66 (0.22-1.91) 2.49 (0.49-12.51) 1.67 (0.30-9.20)
P-value 0.56 0.07 0.46 0.65 0.48
NRTI regimen
AZT-based 1 1 1 1 1
D4T-based 2.17 (0.22-21.47) 1.47 (0.08-25.46) 5.29 (0.44-64.26) 5.62 (0.33-95.76) 6.79 (0.40-116.57)
TDF-based 1.89 (0.62-5.80) 1.25 (0.38-4.06) 2.28 (0.79-6.63) 0.74 (0.17-3.26) 1.37 (0.31-6.03)
P-value 0.56 0.07 0.46 0.65 0.48
NNRTI regimen
EFV-based 1 1 1 1 1
NVP-based 1.27 (0.42-3.81) 1.20 (0.38-3.76) 0.80 (0.29-2.24) 3.96 (0.85-18.52) 4.09 (0.85-19.73)
P-value 0.67 0.76 0.67 0.08 0.08
Smoking
No 1 1 1 NA NA
Yes 5.84 (0.51-67.18) 15.94 (1.13-225.61) 6.06 (0.44-83.99) NA NA
P-value 0.16 0.04 0.18
Alcohol intake
No 1 1 1 1 1
Yes 0.50 (0.18-1.41) 0.24 (0.07-0.74) 0.99 (0.40-2.47) 0.70 (0.21-2.42) 0.58 (0.15-2.17)
P-value 0.19 0.01 0.99 0.58 0.42
Heart condition
No 1 NA 1 NA NA
Yes 0.47 (0.04-6.15) NA 0.25 (0.02-3.24) NA NA
P-value 0.56 0.29
Metabolic condition
No 1 1 1 1 1
Yes 1.42 (0.21-9.79) 12.54 (1.02-153.86) 2.97 (0.38-22.94) 0.67 (0.06-8.08) 1.02 (0.07-14.69)
P-value 0.72 0.048 0.30 0.75 0.99
Special diet
No 1 1 1 1 1
Yes 3.36 (0.56-20.20) 4.19 (0.42-42.07) 1.81 (0.28-11.69) 3.95 (0.45-34.50) 1.06 (0.08-14.17)
P-value 0.19 0.22 0.53 0.22 0.97
ART interruption
No 1 1 1 NA NA
Yes 0.75 (0.05-11.45) 0.89 (0.03-26.83) 7.37 (0.36-149.65) NA NA
P-value 0.84 0.95 0.19

*ART = antiretroviral therapy, **NRTI = nucleotide reverse transcriptase inhibitors, ***NNRTI = non-nucleotide reverse transcriptase inhibitor, AZT = zidovudine, 3TC = lamivudine, TDF = tenofovir, D4T = stavudine, EFV = efavirenz, NVP = nevirapine, NA = not applicable.

Bekolo et al.

Bekolo et al. BMC Public Health 2014 14:236   doi:10.1186/1471-2458-14-236

Open Data