Table 2

Quality assessment of trials of antibiotics for the treatment of Shigella

Quality Assessment

Summary of Findings


Directness

No of events


No of studies

Design

Limitations

Consistency

Generalizability to population of interest

Generalizability to intervention of interest

Intervention

Control

Relative Risk (95%CI)


Clinical Failure (Antibiotics): Moderate Outcome Quality


03[25-27]

RCT

No Control or placebo group, so used treatment failure rates

All suggest benefit

All studies were conducted in developing countries

Hospital based

50

0.18 (0.1, 0.33)b


Bacteriological Failure (Antibiotics): Low Outcome Quality


04[25-28]

RCT

No Control or placebo group, so used treatment failure rates

All suggest benefit

All studies except one were conducted in developing countries

Hospital based

09

0.04 (0.01, 0.12)b


Das et al. BMC Public Health 2013 13(Suppl 3):S10   doi:10.1186/1471-2458-13-S3-S10

Open Data