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Association of blood pressure with development of metabolic syndrome components: a five-year Retrospective Cohort study in Beijing

Da Huo123, Lixin Tao12, Xia Li124, Wei Wang5, Zhaoping Wang6, Dongning Chen6, Huiping Zhu12, Xinghua Yang12, Yanxia Luo12 and Xiuhua Guo12*

Author Affiliations

1 School of Public Health, Capital Medical University, No. 10 Xitoutiao, You’anmen Wai, Fengtai District, Beijing 100069, China

2 Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing 100069, China

3 Institute for Infectious Disease and Endemic Disease Control, Beijing Center for Disease Prevention and Control, No. 16 Hepingli Middle Street, Dongcheng District, Beijing 100013, China

4 Department of Epidemiology and Public Health, University College Cork, Fourth Floor, Western Gate Building, Cork, Ireland

5 Department of Integrated Early Childhood Development, Capital Institute of Pediatrics, No. 2 Yabao Road, Chaoyang District, Beijing 100020, China

6 Physical Examination Department, Beijing Tongren Hospital, Capital Medical University, No. 1 Dongjiao Minxiang, Dongcheng District, Beijing 100730, China

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BMC Public Health 2013, 13:912  doi:10.1186/1471-2458-13-912

Published: 2 October 2013



Raised blood pressure (BP) is associated with the incidence of metabolic syndrome (MetS). It is unknown if subjects with different BP levels may develop certain components of MetS over time. We investigated the incidence of MetS relative to different levels of BP over a 5-year period in a Chinese population in Tongren Hospital, Beijing.


During the period of 2006–2011, we recruited 2,781 participants with no MetS, or self-reported type 2 diabetes, dyslipidemia, hypertension, or cardiovascular disease at baseline. Association rule was used to identify the transitions of MetS components over time.


The incidence of MetS at follow-up was 9.74% for men and 3.21% for women in the group with optimal BP; 10.29% and 7.22%, respectively, in the group with normal BP; 10.49% and 10.84%, respectively, in the group with high-normal BP; and 14.48% and 23.21%, respectively in the group with high BP. The most common transition was from healthy to healthy in the groups with optimal or normal BP (17.9–49.3%), whereas in the high-normal BP group, 16.9-22.1% of subjects with raised BP returned to healthy status or stayed unchanged, while 13.8-21.4% of people with high BP tended to develop raised fasting glucose levels.


The incidence of MetS increased in parallel with the increase in BP. People with optimal and normal BP levels were less susceptible to developing MetS over time, whereas abnormal BP seemed to be a pre-existing phase of MetS. High-normal BP was a crucial status for MetS prevention.

Metabolic syndrome; Blood pressure; Retrospective cohort study; Chinese