Email updates

Keep up to date with the latest news and content from BMC Public Health and BioMed Central.

Open Access Research article

Active pulmonary tuberculosis and latent tuberculosis infection among homeless people in Seoul, South Korea: a cross-sectional study

Chang-Hoon Lee12, Yun-Jeong Jeong23, Eun Young Heo1, Jong Sun Park4, Ji Sun Lee2, Byoung Jun Lee25, Young Sik Park2, Eun Hee Song2, Yun Jung Yang2, Young Soo Cho6, En-hi Cho7, Kyoung-in Na7, Eun-Jeong Oh7, Jin-beom Lee8, Soo-Yeon Oh8, HeeJin Kim8, Chang Min Park9 and Jae-Joon Yim2*

Author affiliations

1 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Republic of Korea

2 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, 103 Daehak-ro, Jongno-gu 110-744, Republic of Korea

3 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Dongguk University Ilsan Medical Center, Gyeonggi-do, Republic of Korea

4 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Gyeonggi-do, Republic of Korea

5 Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Veterans Hospital, Seoul, Republic of Korea

6 Department of Tuberculosis, Seoul Metropolitan Government Seobuk Hospital, Seoul, Republic of Korea

7 Division of HIV and TB control, Korean Centers for Disease Control and Prevention, Seoul, Republic of Korea

8 Programme Cooperation Department, Korean Institute of Tuberculosis, Seoul, Republic of Korea

9 Department of Radiology, Seoul National University College of Medicine, Seoul, Republic of Korea

For all author emails, please log on.

Citation and License

BMC Public Health 2013, 13:720  doi:10.1186/1471-2458-13-720

Published: 5 August 2013

Abstract

Background

The aim of this study was to determine the prevalence rate of latent TB infection (LTBI) and active TB among homeless in Seoul metropolitan city, South Korea, and to compare the TB burden among homeless people with that of a control group.

Methods

The homeless participants were recruited from five sites between October 30, 2009 and April 12, 2010. LTBI was diagnosed through the QuantiFERON(R) TB Gold In-Tube(QFT-GIT) assay and a tuberculin skin test(TST) and, and active PTB was diagnosed based on chest radiography.

Results

Among 313 participants, the prevalence of LTBI was 75.9% (95% CI, 71.1-80.8%) and 79.8% (95% CI, 74.9-84.7%) based on a QFT-GIT assay and the TST, respectively, and that of active PTB was 5.8% (95% CI, 3.2-8.3%). The prevalence of LTBI among homeless participants was about five times higher than controls. Also, the age-specific prevalence rate ratio of active PTB was as high as 24.86.

Conclusions

The prevalence rate of LTBI as well as active PTB among homeless people was much higher than that of the general population in South Korea. Thus, adequate strategies to reduce the TB burden among homeless people are needed.

Keywords:
Tuberculosis; X-rays; Latent-TB infection (LTBI); Prevalence; Active pulmonary TB (PTB); Homeless