Table 5

Schedules for second, third and fourth in-clinic evaluations of smokers
Days and suggested times Sampling Procedure
45, 76, 108
1700 h (check in) Blood, urine Measure BP, PR, RR and temperature; abbreviated physical examination and medical history; illicit drug, alcohol and cotinine testing; pregnancy testing; collection of diary and cigarette butts; clinical laboratory tests; electrocardiography; lung- function tests; dinner
1900 h None Start 24 h urine collection, monitoring of cigarette consumption and collection of filters
2100 h None Snack
46, 77, 109
0700 h Blood Measure BP, PR, RR and temperature; measure creatinine in serum; biomarkers and gene expression
0800 h None Breakfast
1000 h None Administer sensory questionnaire; administer quality-of-life and diet and lifestyle questionnairesa
1200 h None Lunch
1500 h None Measure exhaled CO
1700 h Saliva Cotinine testing; dinner
1900 h None End 24 h urine collection, monitoring of cigarette consumption and collection of filters; dispense interventional products and cigarette butt collection tins for use at home, remind participants of instructions for diet and completion of diaries

BP, blood pressure, PR, pulse rate, RR, respiratory rate, CO, carbon monoxide, aOn day 108–109 visit only; may be conducted on either day.

Shepperd et al.

Shepperd et al. BMC Public Health 2013 13:690   doi:10.1186/1471-2458-13-690

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