Table 1

Parameter values and assumptions used for the Canadian antiviral stockpile model
Item Strain Value (range) Reference(s)
Transmissibility
R0 1957/1958 1.6 (attack rate = 37%) [8,26,34-36]
1968/1969 1.8 (attack rate = 41%) [8,26,34,35,37,38]
1918 2.0 (attack rate = 45%) [8,26,34,35,39,40]
Natural history
Latent period Seasonal 2.1 days [41]
Duration of infection Seasonal 4.8 days [41]
Pre-existing immunity in individuals > years 0% (0 – 40%) Assumption
Clinical characteristics
Proportion symptomatic 1957 60% [8]
Proportion of symptomatic cases seeking medical attention 1957 70% [8]
Vaccination
Vaccine coverage by age group Age group RRFSS (%)
[27]
0-17 60
18-22 62
23-52 54
53-64 65
65+ 75

RRFSS – Rapid Risk Factor Surveillance System.

Attack rates are calculated as base case scenarios in the absence of any interventions.

Greer

Greer BMC Public Health 2013 13:669   doi:10.1186/1471-2458-13-669

Open Data