Table 4

Multiple logistic regression analysis of determinants for normotensive blood pressure values
1. Model: Substances 2. Model: Therapy
Independent variables OR2(95% CI3) OR2(95% CI3)
Sex (ref. male)
   female 1.29 (1.03–1.63) (p = 0.030) 1.33 (1.05–1.67) (p = 0.016)
Age in years (cont. variable)
0.98 (0.97–0.99) (p = 0.001) 0.98 (0.97–0.99) (p = 0.001)
Risk-comorbidity (ref. no)
   yes 0.39 (0.30–0.52) (p < 0.0001) 0.40 (0.30–0.53) (p < 0.0001)
Obesity (ref. no)
   yes 0.60 (0.48–0.76) (p < 0.0001) 0.62 (0.49–0.77) (p < 0.0001)
Active smoker4(ref. no)
   yes 0.97 (0.73–1.30) (p = 0.845) 0.97 (0.73–1.30) (p = 0.839)
Household size (ref. > 1 pers.)
   1 person 1.19 (0.91–1.57) (p = 0.208) 1.19 (0.91–1.57) (p = 0.206)
Antihypertensive therapy(ref. no)
   mono therapy - 0.93 (0.69–1.26) (p = 0.650)
   combination therapy - 1.54 (1.16–2.05) (p = 0.003)
Beta blocker (ref. no)
   yes 1.28 (1.01–1.64) (p = 0.044) -
ACE-inhibitors (ref. no)
   yes 1.04 (0.78–1.38) (p = 0.792) -
Diuretics (ref. no)
   yes 1.32 (0.95–1.84) (p = 0.097) -
Calcium channel blocker (ref. no)
   yes 1.03 (0.76–1.40) (p = 0.841) -
Angiotensin II receptor antag. (ref. no)
   yes 1.13 (0.76–1.67) (p = 0.546) -
Antiadrenergic substances5(ref. no)
   yes 1.16 (0.54–2.48) (p = 0.698) -

1Study participants with blood pressure values ≥140/90 mmHg and/or antihypertensive medication with known hypertension and/or study participants with risk-comorbidity (diabetes, stroke, angina pectoris, and/or myocardial infarction) and blood pressure values ≥130/80 mmHg.

2OR Odds Ratio.

3CI confidence interval.

4Self reported smoking.

5Both peripheral and central active antiadrenergic substances.

Model 1 considers the active substances the patients received, model 2 considers the kind of therapy (mono or combination therapy). Included are all hypertensive patients1 to SHIP-0 with information on the independent variables to SHIP-1 (N = 1749 of in total 1761 hypertensive patients in the SHIP-0 cohort).

van den Berg et al.

van den Berg et al. BMC Public Health 2013 13:594   doi:10.1186/1471-2458-13-594

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