Table 4

Unadjusted and adjusted odds ratios of asthma and allergic symptoms in children aged 7–8 and 13–14 from the Greek-Cypriot and Turkish-Cypriot communities in relation to risk factors projected in the hygiene hypothesis
Children 7–8 years of age
Current wheeze Severe asthma Current eczema Current Rhinoconjuctivitis
Unadjusted OR (95%CI) Adjusted OR† (95% CI) Unadjusted OR (95% CI) Adjusted OR† (95% CI) Unadjusted OR (95% CI) Adjusted OR† (95% CI) Unadjusted OR(95% CI) Adjusted OR† (95% CI)
Older sibling
  1 (Vs None) 0.86 (0.69, 1.07) 0.76 (0.59, 0.97) 1.08 (0.77, 1.51) 0.80 (0.55, 1.16) 0.87 (0.63, 1.20) 0.70 (0.48, 1.00) 0.87 (0.61. 1.23) 0.76 (0.51, 1.11)
  ≥2 (Vs None) 0.83 (0.63, 1.08) 0.72 (0.53, 0.98) 0.82 (0.52, 1.27) 0.56 (0.33, 0.91) 0.48 (0.29, 0.75) 0.36 (0.20, 0.61) 0.97 (0.63, 1.46) 0.77 (0.47, 1.22)
Farm animal at home 1.11 (0.62, 1.87) 0.99 (0.54, 1.72) 1.13 (0.46, 2.36) 0.97 (0.38, 2.10) 1.26 (0.48, 2.74) 1.33 (0.49, 3.04) 1.26 (0.52, 2.62) 1.02 (0.40, 2.21)
Area of residence
  Sub-rural (Vs Rural) 1.04 (0.79, 1.37) 1.09 (0.82, 1.45) 1.40 (0.92, 2.13) 1.49 (0.96, 2.31) 1.01 (0.64, 1.61) 1.12 (0.69, 1.80) 1.03 (0.67, 1.57) 1.08 (0.70, 1.68)
  Urban (Vs Rural) 0.87 (0.69, 1.12) 0.87 (0.67, 1.13) 1.04 (0.70, 1.54) 1.02 (0.67, 1.56) 1.20 (0.82, 1.79) 1.20 (0.79, 1.85) 0.89 (0.61, 1.30) 0.83 (0.56, 1.26)
Bedroom sharing 1.09 (0.90, 1.33) 1.20 (0.95, 1.52) 1.61 (1.18, 2.20) 1.69 (1.17, 2.43) 1.00 (0.75, 1.36) 1.29 (0.90, 1.86) 1.16 (0.85, 1.58) 1.17 (0.82, 1.69)
Nursery attendance 1.25 (0.84, 1.96) 1.28 (0.85, 2.03) 0.81 (0.47, 1.53) 0.85 (0.49, 1.62) 0.88 (0.53, 1.58) 0.84 (0.49, 1.52) 0.97 (0.55, 1.92) 1.05 (0.58, 2.10)
Children 13–14 years of age
Current wheeze Severe asthma Current eczema Current Rhinoconjuctivitis
Unadjusted OR (95%CI) Adjusted OR(95% CI) Unadjusted OR (95% CI) Adjusted OR(95% CI) Unadjusted OR (95% CI) Adjusted OR(95% CI) Unadjusted OR (95% CI) Adjusted OR(95% CI)
Older sibling
  1 (Vs None) 0.87 (0.65, 1.16) 0.87 (0.64, 1.19) 1.00 (0.67, 1.48) 1.03 (0.66, 1.58) 0.86 (0.54, 1.37) 0.84 (0.50, 1.39) 1.33 (1.00. 1.77) 1.29 (0.95, 1.76)
  ≥2 (Vs None) 0.82 (0.59, 1.13) 0.90 (0.64, 1.26) 0.86 (0.53, 1.35) 0.95 (0.57, 1.55) 1.43 (0.92, 2.24) 1.40 (0.86, 2.27) 1.59 (1.17, 2.15) 1.41 (1.02, 1.96)
Farm animal at home 0.35 (0.04, 0.94) 0.39 (0.10, 1.05) 0.94 (0.28, 2.30) 0.78 (0.19, 2.19) 0.88 (0.21, 2.42) 0.94 (0.23, 2.66) 1.15 (0.58, 2.08) 1.03 (0.49, 1.94)
Area of residence
  Sub-rural (Vs Rural) 1.52 (1.05, 2.20) 1.64 (1.11, 2.42) 1.61 (0.97, 2.71) 1.77 (1.02, 3.10) 0.99 (0.56, 1.72) 1.04 (0.56, 1.88) 0.68 (0.47, 0.96) 0.75 (0.51, 1.10)
  Urban (Vs Rural) 1.37 (1.00, 1.90) 1.44 (1.02, 2.05) 1.42 (0.91, 2.26) 1.46 (0.90, 2.43) 1.03 (0.66, 1.65) 1.29 (0.80, 2.12) 0.89 (0.68, 1.16) 0.98 (0.73, 1.33)

† Adjusted for each other as well as community (G/C and T/C), gender, parents’ nationality, parents’ level of education, family history of allergies, animals at home, passive smoking, maternal smoking during pregnancy, mode of delivery, birth weight and exclusive breastfeeding duration.

‡ Adjusted for each other as well as community (G/C and T/C), gender, parents’ nationality, parents’ level of education, family history of allergies, animals at home and passive smoking at home. Bedroom sharing, nursery attendance, maternal smoking during pregnancy, mode of delivery, birth weight and exclusive breastfeeding duration were not available for the 13–14 year-old children.

Lamnisos et al.

Lamnisos et al. BMC Public Health 2013 13:585   doi:10.1186/1471-2458-13-585

Open Data