Table 3

Associations of sex-specific serum GGT and UA quartiles with IFG
Subgroup IFG OR (95% CI)
(n) n (%) Model 1 Model 2 Model 3
Males
GGT
  Q1 (<23 U/L) 312 59 (18.9%) 1 (ref) 1 (ref) 1 (ref)
  Q2 (23–35 U/L) 305 78 (25.6%) 1.62 (1.06–2.50) 1.50 (0.97–2.31) 1.48 (0.94–2.29)
  Q3 (35–57 U/L) 291 94 (32.3%) 0.91 (0.62–1.35) 2.08 (1.32–3.25) 1.99 (1.26–3.15)
  Q4 (>57 U/L) 303 102 (33.7%) 1.01 (0.68–1.51) 2.14 (1.33–3.45) 1.90 (1.16–3.12)
  P for trend 0.000 0.001 0.007
UA
  Q1 (<296 U/L) 225 71 (31.6%) 1 (ref) 1 (ref) 1 (ref)
  Q2 (296–344 U/L) 236 67 (28.4%) 0.93 (0.61–1.40) 0.84 (0.55–1.27) 0.84 (0.55–1.28)
  Q3 (344–402 U/L) 221 87 (39.4%) 1.43 (0.96–2.13) 1.23 (0.82–1.85) 1.19 (0.79–1.81)
  Q4 (>402 U/L) 194 107 (55.2%) 1.91 (1.28–2.84) 1.52 (1.00–2.31) 1.47 (0.96–2.25)
  P for trend 0.000 0.013 0.027
Females
GGT
  Q1 (<15 U/L) 409 38 (9.3%) 1 (ref) 1 (ref) 1 (ref)
  Q2 (15 ~ 20 U/L) 338 49 (14.5%) 1.76 (1.06–2.94) 1.65 (0.99–2.78) 1.58 (0.94–2.67)
  Q3 (20 ~ 30 U/L) 366 74 (20.2%) 2.69 (1.63–4.45) 2.44 (1.46–4.08) 2.26 (1.33–3.83)
  Q4 (>30 U/L) 370 98 (26.5%) 3.52 (2.17–5.72) 3.19 (1.93–5.27) 2.86 (1.70–4.82)
  P for trend 0.000 0.000 0.000
UA
  Q1 (<220 U/L) 330 36 (10.9%) 1 (ref) 1 (ref) 1 (ref)
  Q2 (220–262 U/L) 325 42 (12.9%) 1.16 (0.71–1.90) 1.09 (0.66–1.80) 1.08 (0.65–1.78)
  Q3 (262–310 U/L) 298 71 (24.6%) 1.82 (1.15–2.90) 1.69 (1.05–2.71) 1.61 (0.99–2.61)
  Q4 (>310 U/L) 262 108 (41.2%) 2.70 (1.72–4.24) 2.41 (1.52–3.84) 2.22 (1.37–3.58)
  P for trend 0.000 0.000 0.000

1 Abbreviations: GGT, γ-Glutamyltransferase; UA, Uric acid; IFG, Impaired fasting glucose; OR, Odds ratio; CI, Confidence interval.

2 Multivariate logistic regression models were used to estimate the ORs and 95% CIs.

Model 1: adjusted for age, ethnicity, smoking, alcohol consumption, physical labor.

Model 2: Model 1 plus body mass index, waist circumference, systolic blood pressure, and diastolic blood pressure.

Model 3: Model 2 plus total cholesterol, triglyceride, high-density lipoprotein–cholesterol, and low-density lipoprotein–cholesterol.

Wu et al.

Wu et al. BMC Public Health 2013 13:294   doi:10.1186/1471-2458-13-294

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