Table 1

Tuberculin skin test (TST) & Cytokines production in whole blood cultures [ESAT-6/CFP-10 & PPD] in the study population at screening
Variables House-Hold contacts Community controls** p value
(n = 98)¤ (n = 186)
  TST (mean ± SD) 5 ±6 2 ±3 0.000*
< 5 mm 59 (60.2%) 139 (83.2%) 0.000*
5 - 9 mm 12 (12.2%) 13 (7.8%) 0.04*
10 - 14 mm 13 (13.2%)§ 14 (8.4%) 0.1
≥ 15 mm 14 (14.4%)§ 01 (0.6%) 0.000*
IFN-γ Mean level IU/ml:
  Purified Protein Derivative:
Mean ± SD 0.5 ± 0.6 0.3 ± 0.4 0.4
< 0.35 57/98 (58.2%) 130/186 (69.9%) 0.06
0.35-1.0 28/98 (28.6%) 44/186 (23.6%) 0.1
1.1-2.0 13/98 (13.2%) 12/186 (6.5%) 0.3
  ESAT-6 + CFP −10 ± TB7•7:
Mean ± SD 0.5 ± 0.7 0.2 ± 0.2 0.000*
< 0.35 56/98 (57.1%) 136/186(73.2%) 0.03*
0.35 - 1.0 18/98 (18.4%)§ 41/186 (22.2%) 0.01*
1.1 - 2.0 24/98 (24.5%)§ 09/186 (4.6%) 0.2

Continuous variable are expressed as means ± SD. *Significant difference (p < 0.05).

§There was a low correlation between IFN-γ level >0.35 IU/ml and TST ≥10 mm (r = 0.4).

All volunteers had history of BCG vaccination that was confirmed in the majority (>85%) by presence of a scar. **Nineteen CCs did not report for TST reading.

Shakak et al.

Shakak et al. BMC Public Health 2013 13:1128   doi:10.1186/1471-2458-13-1128

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