Table 6

Association of various factors with chronic kidney disease (eGFR <60 mL/min/1.73 m2) based on different estimating equations
MDRD GFR CKD-Epi CsyC-based CKD
crude adjusteda crude adjusteda crude adjusteda
Age 65–69 1.00 (referent) 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent)
70–79 1.60 (1.18; 2.16) 1.52 (1.11; 2.10) 2.09 (1.49; 2.91) 1.98 (1.40; 2.81) 3.36 (1.75; 6.45) 3.30 (1.64; 6.67)
≥80 3.57 (2.61; 4.89) 3.33 (2.37; 4.74) 6.41 (4.55; 9.03) 6.01 (4.14; 8.73) 13.66 (7.25; 25.73) 13.94 (6.95; 27.98)
Gender female 1.47 (1.18; 1.83) 1.63 (1.23; 2.16) 1.15 (0.92; 1.43) 1.23 (0.92; 1.65) 1.04 (0.77; 1.39) 0.89 (0.58; 1.34)
Family status Married 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent)
widowed 1.94 (1.51; 2.49) 1.24 (0.93; 1.65) 2.09 (1.63; 2.69) 1.29 (0.96; 1.74) 2.11 (1.54; 2.90) 1.17 (0.79; 1.74)
other 1.29 (0.89; 1.86) 1.12 (0.75; 1.67) 1.40 (0.97; 2.03) 1.33 (0.88; 2.00) 1.29 (0.78; 2.14) 1.34 (0.75; 2.38)
Duration of ≤9 yrs 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent)
school education 10–11 yrs 1.01 (0.77; 1.31) 1.11 (0.83; 1.47) 1.00 (0.76; 1.31) 1.13 (0.84; 1.52) 1.02 (0.72; 1.46) 1.17 (0.78; 1.75)
≥12 yrs 0.96 (0.72; 1.29) 1.18 (0.86; 1.63) 0.93 (0.69; 1.25) 1.11 (0.80; 1.54) 0.72 (0.47; 1.10) 0.85 (0.53; 1.37)
Alcohol consumption daily 0.49 (0.36; 0.68) 0.69 (0.48; 1.01) 0.54 (0.39; 0.75) 0.66 (0.45; 0.97) 0.43 (0.29; 0.64) 0.40 (0.24; 0.66)
several time per week or per month 0.54 (0.40; 0.72) 0.72 (0.52; 1.00) 0.55 (0.41; 0.74) 0.70 (0.50; 0.98) 0.37 (0.26; 0.54) 0.39 (0.25; 0.60)
<1 time per month 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent)
never 0.81 (0.25; 2.62) 0.57 (0.17; 1.95) 1.25 (0.39; 3.99) 0.93 (0.28; 3.14) 0.97 (0.26; 3.71) 0.68 (0.16; 2.91)
Smoking status smoker 0.56 (0.37; 0.86) 0.73 (0.46; 1.16) 0.61 (0.40; 0.94) 0.77 (0.48; 1.24) 0.85 (0.50; 1.45) 1.11 (0.58; 2.12)
former smoker 0.91 (0.73; 1.14) 1.04 (0.79; 1.35) 0.96 (0.77; 1.21) 0.99 (0.75; 1.31) 0.89 (0.66; 1.21) 0.83 (0.56; 1.22)
never-smoker 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent) 1.00(referent)
Body Mass Index ≥30 kg/m2, n (%) 1.57 (1.22; 2.00) 1.48 (1.13; 1.94) 1.51 (1.18; 1.93) 1.52 (1.15; 2.01) 1.87 (1.37; 2.56) 1.98 (1.37; 2.85)
History of Co-morbidity, hypertension 1.60 (1.29; 1.99) 1.28 (1.00; 1.63) 1.59 (1.27; 1.98) 1.23 (0.96; 1.59) 2.08 (1.53; 2.84) 1.54 (1.07; 2.21)
myocardial infarct 2.40 (1.66; 3.46) 2.18 (1.45; 3.26) 2.84 (1.96; 4.10) 2.40 (1.59; 3.62) 3.23 (2.15; 4.84) 2.22 (1.39; 3.56)
heart failure 1.49 (1.11; 2.01) 1.12 (0.80; 1.55) 1.45 (1.08; 1.96) 1.03 (0.74; 1.45) 2.41 (1.70; 3.41) 1.90 (1.27; 2.84)
diabetes 1.59 (1.17; 2.15) 1.37 (0.98; 1.92) 1.43 (1.09; 1.94) 1.14 (0.80; 1.62) 1.67 (1.14; 2.44) 1.14 (0.74; 1.77)

a Multivariate logistic regression model and 95% confidence interval (95% CI) adjusted for gender, age, family status, duration of school education, alcohol consumption, smoking status, adipositas and history of co-morbidity (hypertension, myocardial infarction, heart failure, diabetes).

Rothenbacher et al.

Rothenbacher et al. BMC Public Health 2012 12:343   doi:10.1186/1471-2458-12-343

Open Data