Table 3

Adjusted HRs and PARs of metabolic disorders for all-cause and CVD-related mortality in women stratified by menopausal status (N = 1143)

All-cause mortality

Peri-menopausal

Post-menopausal


45 ≤ Age < 55

Age ≥ 55


Death (%)(n = 15)

Adj HR†

(95% CI) ‡

PAR (%)

(95% CI)‡

Death

(%)(n = 63)

Adj HR†

(95% CI) ‡

PAR (%)

(95% CI)‡


MetS

4 (26.7)

1.70 (0.33-4.86)

13.4 (1.6-35.3)

35 (55.6)

1.89 (1.05-3.59)*

19.5 (4.1-32.9)


High WC

8 (53.3)

2.33 (0.66-10.90)

26.5 (3.2-51.6)

46 (73.0)

1.48 (0.79-3.44)

16.6 (1.5-39.4)


AH

6 (40.0)

2.48 (0.64-9.38)

25.0 (3.0-47.1)

42 (66.7)

2.14 (1.21-4.27)*

33.2 (11.6-50.6)


DM

0 (0.0)

N/A§

N/A§

22 (34.9)

1.99 (1.02-3.64)*

11.8 (2.18-20.0)


High TG

3 (20.0)

1.64 (0-4.70)

9.1 (0.7-26.7)

17 (27.0)

1.20 (0.64-2.31)

3.2 (0.3-13.5)


Low HDL-C

2 (13.3)

0.61 (0-2.21)

N/A§

21 (33.3)

1.12 (0.58-1.97)

2.9 (0.4-16.2)


CVD-related mortality


Peri-menopausal

Post-menopausal


45 ≤ Age < 55

Age ≥ 55


Death (%)

(n = 3)

Adj HR†

(95% CI) ‡

PAR (%)

(95% CI)‡

Death (%)

(n = 28)

Adj HR†

(95% CI) ‡

PAR (%)

(95% CI)‡


MetS

2 (66.7)

6.21 (N/A§)

41.9 (4.3-86.8)

18 (64.3)

2.95 (1.39-8.71)*

42.5 (19.4-64.7)


High WC

3 (100)

N/A§

N/A§

22 (78.6)

3.38 (1.52-15.1)*

47.8 (21.2-71.3)


AH

2 (66.7)

6.44 (N/A§)

52.8 (4.0-100)

18 (64.3)

1.93 (0.88-5.50)

36.0 (6.37-68.1)


DM

0

N/A§

N/A§

11 (39.3)

2.78 (1.16-7.31)*

22.8 (4.99-38.6)


High TG

2 (66.7)

11.5 (N/A§)

45.6 (11.2-85.7)

9 (32.1)

1.65 (0.51-4.88)

11.4 (1.4-30.4)


Low HDL-C

1 (33.3)

3.96 (N/A§)

28.0 (2.99-75.0)

15 (53.6)

2.51 (1.06-6.11)*

24.5 (5.22-42.3)


†: CAD, stroke, BMI, alcohol drinking, smoking, betel nut chewing, exercise, and income were adjusted for in the model.

‡: The 95% CI obtained by taking the 2.5 and 97.5 percentiles of the recalculated PARs among one thousand bootstrapped datasets.

§: N/A: not available. The adjusted HR was less than 1 due to small number of observations, yielding a negative corresponding PAR.

#: CVD-related mortality (ICD-9th revision codes 250, 390-398, and 401-441).

BMI, body mass index; CAD, coronary artery disease; CI, confidence interval; CVD, cardiovascular disease; DM, diabetes mellitus; AH, arterial hypertension; HDL-C, high-density lipoprotein cholesterol; HR, hazard ratio; MetS, metabolic syndrome; PAR, population attributable risk; TG, triglycerides; WC, waist circumference

Wang et al. BMC Public Health 2012 12:111   doi:10.1186/1471-2458-12-111

Open Data