Table 6 

Application of standardized rules for choice of final outcome to estimate effect of breastfeeding on the reduction of diarrhea mortality 

Outcome Measures 
Application of Standard Rules 



05 months* 

Diarrhea Incidence 
n=3; 1594 events The risk of incident diarrhea is 1.26 (0.811.95) for predominant BF; 1.68 (1.032.76) for partial BF; 2.65 (1.724.07) for not BF as compared to EBF 
Rule 2: APPLY 
Diarrhea Mortality 
n=2; 80 events The risk of diarrhea mortality is 2.28 (0.856.13) for predominant BF; 4.62 (1.8111.76) for partial BF; 10.52 (2.7939.6) for not BF as compared to EBF 



611 months 

Diarrhea Incidence 
n=2; 646 events The risk of incident diarrhea is 1.32 (1.061.63) for not BF as compared to any BF 
Rule 2: APPLY 
Diarrhea Mortality 
n=2; 84 events The risk of diarrhea mortality is 1.47 (0.673.25) for not BF as compared to any BF 



1223 months 

Diarrhea Incidence 
n=0; use estimate for 611 mos: n=2; 646 events The risk of incident diarrhea is 1.32 (1.061.63) for not BF as compared to any BF 
Rule 2: APPLY 
Diarrhea Mortality 
n=2; 84 events The risk of diarrhea mortality is 2.57 (1.106.01) for not BF as compared to any BF 



*Evaluating events for studies where reference category is EBF 

Lamberti et al. BMC Public Health 2011 11(Suppl 3):S15 doi:10.1186/1471245811S3S15 