Open Access Open Badges Study protocol

Rationale and methods of the cardiometabolic valencian study (escarval-risk) for validation of risk scales in mediterranean patients with hypertension, diabetes or dyslipidemia

Vicente Gil-Guillen1, Domingo Orozco-Beltran14*, Josep Redon2, Salvador Pita-Fernandez3, Jorge Navarro-Pérez2, Vicente Pallares1, Francisco Valls5, Carlos Fluixa6, Antonio Fernandez7, Jose M Martin-Moreno8, Manuel Pascual-de-la-Torre9, Jose L Trillo9, Ramon Durazo-Arvizu10, Richard Cooper10, Marta Hermenegildo9 and Luis Rosado9

Author Affiliations

1 University Miguel Hernandez. Department of Clinical Medicine. San Juan de Alicante, Spain

2 University of Valencia. Department of Medicine. Valencia, Spain

3 University A Coruña. A Coruña, Spain

4 Unión de Mutuas. Castellón, Spain

5 Centro de Salud Beniganim. Valencia, Spain

6 Centro de Salud Benimaclet. Valencia, Spain

7 ESCARVAL Project. Valencia, Spain

8 Director of Programme Management WHO Regional Office for Europe. Copenhagen, Denmark

9 Department of Health; Valencia Government. Valencia, Spain

10 Loyola University of Chicago. Stricht School of Medicine. Department of Preventive Medicine and Epidemiology. Chicago, USA

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BMC Public Health 2010, 10:717  doi:10.1186/1471-2458-10-717

Published: 22 November 2010



The Escarval-Risk study aims to validate cardiovascular risk scales in patients with hypertension, diabetes or dyslipidemia living in the Valencia Community, a European Mediterranean region, based on data from an electronic health recording system comparing predicted events with observed during 5 years follow-up study.


A cohort prospective 5 years follow-up study has been designed including 25000 patients with hypertension, diabetes and/or dyslipidemia attended in usual clinical practice. All information is registered in a unique electronic health recording system (ABUCASIS) that is the usual way to register clinical practice in the Valencian Health System (primary and secondary care). The system covers about 95% of population (near 5 million people). The system is linked with database of mortality register, hospital withdrawals, prescriptions and assurance databases in which each individual have a unique identification number. Diagnoses in clinical practice are always registered based on IDC-9. Occurrence of CV disease was the main outcomes of interest. Risk survival analysis methods will be applied to estimate the cumulative incidence of developing CV events over time.


The Escarval-Risk study will provide information to validate different cardiovascular risk scales in patients with hypertension, diabetes or dyslipidemia from a low risk Mediterranean Region, the Valencia Community.