Table 3

Summary of the validation parameters for the LC-MS/MS methods for the determination of residual antibiotics in water samples from a hospital in Ujjain, India

Antibiotics

Correlation coefficient r2

Coefficient of Variation (%RSD)

LOD μg/l

LOQ μg/l

% Recovery n = 5


Interday n = 6

Intraday n = 6


Amoxicillin

0.994

5.2

5.6

0.5

1.0

85 (%RSD 5.6)

Ceftrixone

0.997

2.1

1.8

2.5

5.0

84 (%RSD 4.1)

Amikacin

0.990

4.8

4.3

0.25

0.5

92 (%RSD 3.8)

Ofloxacin

0.999

3.1

2.57

0.01

0.025

95 (%RSD 3.7)

Ciprofloxacin

0.999

3.2

3.03

0.01

0.025

98 (%RSD 4.5)

Norfloxacin

0.999

3.4

3.02

0.01

0.025

90 (%RSD 3.2)

Levofloxacin

0.999

3.12

2.96

0.01

0.025

93 (%RSD 2.8)


LOD: Limit of detection; LOQ: Limit of quantification

Diwan et al. BMC Public Health 2010 10:414   doi:10.1186/1471-2458-10-414

Open Data