Table 3

Summary of effect of lower age at menarche on 15-year survival

Complete case analyses (n = 942)

Multiple imputation analyses (n = 1,031)

Model

HR

95% CI

P-value

HR

95% CI

P-value


1: Age adjusted

Menarche ≥ 12y

1.00

1.00

Menarche < 12y

1.35

1.05 - 1.73

0.018

1.30

1.02 - 1.65

0.032

2: Age + Health adjusteda

Menarche ≥ 12y

1.00

1.00

Menarche < 12y

1.31

1.02 - 1.68

0.037

1.26

0.98 - 1.61

0.070

3: Age + Health + Lifestyle adjustedb

Menarche ≥ 12y

1.00

1.00

Menarche < 12y

1.31

1.02 - 1.69

0.035

1.29

1.01 - 1.64

0.045

4: Age + Health + Lifestyle + Reproductive adjustedc

Menarche ≥ 12y

1.00

1.00

Menarche < 12y

1.28

0.99 - 1.65

0.062

1.25

0.98 - 1.60

0.074


a: Overall analyses adjusted for age group, place of residence, and health variables (self-rated health, cognitive function, number of morbid conditions).

b: Overall analyses adjusted for age group, place of residence, health variables, and lifestyle variables (smoking status, exercise status, BMI category).

c: Overall analyses adjusted for age group, place of residence, health variables, lifestyle variables, and reproductive variables (parity, age at menopause, number of reproductive years)

Giles et al. BMC Public Health 2010 10:341   doi:10.1186/1471-2458-10-341

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