Table 1

Patient baseline characteristics for switchers and continuers of the initial antipsychotic - analysis sample

Characteristic

Patients continuing with their initial antipsychotics (N = 376)

Patients switching antipsychotics (N = 156)

p-value


Male, %

66.5

51.9

.002

Age, mean (SD), y

42.6 (12.0)

42.8 (12.8)

.877

Age of onset, mean (SD), y

22.8 (10.3)

22.6 (9.2)

.802

Unemployed

79.0

78.9

.971

Race, %

Caucasian

54.8

53.9

.843

African descent

33.0

34.0

.824

Other

12.2

12.2

.986

Diagnosis, %

Schizophrenia

65.7

61.5

.362

Schizoaffective

25.0

28.2

.443

Schizophreniform

9.3

10.3

.735

Comorbidities, %

MDD

13.3

14.1

.805

Anxiety

6.1

3.2

.171

Substance abuse

32.2

25.8

.146


Patients continuing with their initial antipsychotics (N = 376)

Patients switching antipsychotics (N = 156)

p-value


Baseline PANSS total, mean (SD)

88.9 (20.6)

84.5 (19.3)

.023

Hospitalization in prior year

30.2

24.5

.191


Abbreviations: MDD, major depressive disorder; PANSS, positive and negative syndrome scale.

P-values based on chi-square and t-tests.

Faries et al. BMC Psychiatry 2009 9:54   doi:10.1186/1471-244X-9-54

Open Data