Open Access Highly Accessed Research article

Proteome analysis of schizophrenia patients Wernicke's area reveals an energy metabolism dysregulation

Daniel Martins-de-Souza123*, Wagner F Gattaz1, Andrea Schmitt4, José C Novello2, Sérgio Marangoni2, Christoph W Turck3 and Emmanuel Dias-Neto15

Author Affiliations

1 Laboratório de Neurociências, Instituto de Psiquiatria, Faculdade de Medicina da USP, Rua Dr. Ovídio Pires de Campos, no 785, São Paulo, SP, CEP 05403-010, Brazil

2 Max Planck Institute of Psychiatry, Kraepelinstrasse 2, D-80804, Munich, Germany

3 Departamento de Bioquímica, Instituto de Biologia, UNICAMP, CEP 13083-970, Campinas, SP, Brazil

4 Department of Psychiatry, Von Siebold Str. 5, University of Goettingen, 37075 Goettingen, Germany

5 University of Texas, MD Anderson Cancer Center, 1515 Holcombe Blvd, 77030, Houston, Texas, USA

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BMC Psychiatry 2009, 9:17  doi:10.1186/1471-244X-9-17

Published: 30 April 2009

Additional files

Additional file 1:

Table 1. Patient and control clinical data. Using Mann-Whitney test, we found no significant differences between patients and controls for age (p = 0.5959), PMI (p = 0.2888) and pH (p = 0.7237).

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Additional file 2:

Table 2. Proteins regulated in schizophrenia samples, classified according to their biological and molecular function. The accession numbers are from the Swiss-Prot database.

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