|
Types of intervention trial and year of publication |
||||
| Type of trial |
1991 |
1995 |
2000 |
Total |
| n = 25 (%) |
n = 45 (%) |
n = 107 (%) |
n = 177 (%) |
|
|
|
||||
| Drug vs drug |
13 (52) |
20 (44) |
56 (52) |
89 (50) |
| Drug vs non-active (eg placebo) |
4 (16) |
9 (20) |
20 (19) |
33 (19) |
| Drug vs psychosocial |
- |
- |
7 (7) |
7 (4) |
| Drug vs biological non-drug (eg ECT) |
2 (8) |
2 (4) |
2 (2) |
6 (3) |
| Drug vs mixed (eg placebo AND psychotherapy) |
- |
- |
1 (<1) |
1 (<1) |
| Drug dose finding |
1 (4) |
2 (4) |
1 (<1) |
4 (2) |
| Total trials involving drugs |
20 (80) |
33 (73) |
87 (81) |
140 (80) |
| Biological non-drug vs biological non-drug |
1 (4) |
2 (4) |
3 (3) |
6 (3) |
| Psychosocial vs psychosocial |
4 (16) |
4 (9) |
5 (5) |
13 (7) |
| Psychosocial vs non-active |
3 (7) |
8 (7) |
11 (6) |
|
| Biological non-drug vs non-active |
1 (2) |
3 (5) |
4 (2) |
|
|
ECT = electroconvulsive therapy | ||||
Sheriff et al. BMC Psychiatry 2008 8:69 doi:10.1186/1471-244X-8-69 |
||||