|
Reason for Sertindole Discontinuation during Study Follow-up (682 patients), with type of previously taken treatment |
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| Total N (%) |
||
|
|
||
| Reason for Stopping |
Beforea |
Afterb |
|
|
||
| Sertindole suspension and Named Patient Use restrictions |
176 (35.3%) |
49 (26.8%) |
| Typical antipsychotic(s)c |
50 (25.1%) |
28 (31.5%) |
| At least one atypical antipsychoticd |
49 (31.6%) |
15 (20.8%) |
|
|
||
| Patient desire to stop |
127 (25.5%) |
50 (27.3%) |
| Typical antipsychotic(s)c |
71 (35.7%) |
26 (29.2%) |
| At least one atypical antipsychoticd |
39 (25.2%) |
18 (25.0%) |
|
|
||
| Lack of efficacy |
64 (12.8%) |
39 (21.3%) |
| Typical antipsychotic(s)c |
28 (14.1%) |
17 (19.1%) |
| At least one atypical antipsychoticd |
23 (14.8%) |
19 (26.4%) |
|
|
||
| Adverse Event(s) |
58 (11.6%) |
19 (10.4%) |
| Typical antipsychotic(s)c |
26 (13.1%) |
10 (11.2%) |
| At least one atypical antipsychoticd |
20 (12.9%) |
9 (12.5%) |
|
|
||
| Other reasons |
74 (14.8%) |
26 (14.2%) |
| Typical antipsychotic(s)c |
24 (12.1%) |
8 (9.0%) 11 |
| At least one atypical antipsychoticd |
24 (15.5%) |
(15.3%) |
|
|
||
| Total |
499 (100.0%) |
183 (100.0%) |
|
a For 2 patients, reason for stopping sertindole treatment was missing. b For 1 patient, reason for stopping sertindole treatment was missing. c For 129 patients, the name of the antipsychotic given before sertindole treatment was missing and 48 patients had no antipsychotic treatment before sertindole. d For 8 patients, the name of the antipsychotic given before sertindole treatment was missing and 25 patients had no antipsychotic treatment before sertindole. | ||
Lançon et al. BMC Psychiatry 2008 8:57 doi:10.1186/1471-244X-8-57 |
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