Table 3

Correlation analysis of qPCR expression levels

Gene Name

SERPINA3

IFITM2

IFITM3

GBP1

MAG

SCD

TF


SERPINA3

1.00

0.60

0.66

0.39

0.16

0.16

0.12

IFITM2

0.58

1.00

0.91

0.56

0.00

0.08

-0.04

IFITM3

0.60

0.90

1.00

0.60

0.11

0.16

0.02

GBP1

0.39

0.51

0.62

1.00

0.22

0.31

0.23

MAG

-0.05

-0.16

-0.13

-0.14

1.00

0.88

0.93

SCD

0.14

-0.04

-0.04

-0.06

0.64

1.00

0.89

TF

0.14

0.01

-0.03

-0.09

0.76

0.81

1.00


The co-expression patterns of genes that were differentially expressed in schizophrenic subjects and/or varied between schizophrenic subgroups (IFITM2, IFITM3, SERPINA3, GBP1, SCD, MAG and TF) were explored for schizophrenic subjects and controls respectively. All pair-wise Pearson correlation coefficients were calculated on pPCR expression levels that remained after removing systematic variation that was due to factor such as diagnosis, schizophrenic subgroup, brain bank, age, post mortem time and reference gene expression (see details in Methods). Correlation of mRNA levels in the frontal cortex of schizophrenic subjects (below diagonal) and control individuals (above diagonal). Pearson correlation coefficients that were significant at the 0.01 levels have been outlined in bold.

Saetre et al. BMC Psychiatry 2007 7:46   doi:10.1186/1471-244X-7-46

Open Data