Table 1 |
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|
SCID-I-II principal diagnosis of 183 healthy siblings, and SCID-I diagnosis of 111 individuals from the comparison group. In brackets number of those 14 siblings who had psychotic symptoms before 1991. |
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|
Isolate siblings |
Comparison group |
|
|
|
||
|
N |
183 |
111 |
|
Psychotic disorders |
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|
Schizophrenia |
1 (1) 0.5% |
1 0.9% |
|
Schizoaffective disorder |
6 (2) 3.3% |
|
|
Delusional disorder |
3 (1) 1.6% |
|
|
Psychotic disorder NOS |
8 (4) 4.4% |
|
|
Alcohol-induced psychotic disorders |
4 (3) 2.2% |
1 0.9% |
|
Other substance-induced psychotic disorders |
2 (1) 1.1% |
|
|
Major depressive disorder with psychotic features |
4 (1) 2.2% |
|
|
Bipolar disorder I |
2 (1) 1.1% |
|
|
Other mental disorders |
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|
Other depressive disorders |
28 15.3% |
21 18.9% |
|
Personality disorders A * |
7 3.8% |
not assessed |
|
Personality disorders B-C* |
4 2.2% |
not assessed |
|
Alcohol use disorders |
7 3.8% |
14 12.6% |
|
Anxiety disorders |
22 12.0% |
8 7.2% |
|
Other |
1 0.5% |
|
|
Diagnosis |
99 54.1% |
45 40.5% |
|
No diagnosis |
84 45.9% |
66 59.5% |
|
|
||
|
Total |
183 99.9% |
111 100% |
|
|
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|
*5 siblings had SCID-II personality disorder without other diagnosis. Siblings had 43 (23.5%) co-morbid diagnoses: 15 (8.2%) alcohol use, 15 anxiety (8.2%), and 6 (3.3%) other depressive disorders, 5 (2.7%) personality disorders (2 cluster A and 3 cluster B-C), one anxiolytic dependence disorder and one hypochondriasis. Comparison group had 10 (9.0%) co-morbid diagnoses: 5 anxiety and 5 alcohol use disorders. |
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Arajärvi et al. BMC Psychiatry 2006 6:6 doi:10.1186/1471-244X-6-6 |
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