Table 1

SCID-I-II principal diagnosis of 183 healthy siblings, and SCID-I diagnosis of 111 individuals from the comparison group. In brackets number of those 14 siblings who had psychotic symptoms before 1991.

Isolate siblings

Comparison group


N

183

111

Psychotic disorders

Schizophrenia

1 (1) 0.5%

1 0.9%

Schizoaffective disorder

6 (2) 3.3%

Delusional disorder

3 (1) 1.6%

Psychotic disorder NOS

8 (4) 4.4%

Alcohol-induced psychotic disorders

4 (3) 2.2%

1 0.9%

Other substance-induced psychotic disorders

2 (1) 1.1%

Major depressive disorder with psychotic features

4 (1) 2.2%

Bipolar disorder I

2 (1) 1.1%

Other mental disorders

Other depressive disorders

28 15.3%

21 18.9%

Personality disorders A *

7 3.8%

not assessed

Personality disorders B-C*

4 2.2%

not assessed

Alcohol use disorders

7 3.8%

14 12.6%

Anxiety disorders

22 12.0%

8 7.2%

Other

1 0.5%

Diagnosis

99 54.1%

45 40.5%

No diagnosis

84 45.9%

66 59.5%


Total

183 99.9%

111 100%


*5 siblings had SCID-II personality disorder without other diagnosis.

Siblings had 43 (23.5%) co-morbid diagnoses: 15 (8.2%) alcohol use, 15 anxiety (8.2%), and 6 (3.3%) other depressive disorders, 5 (2.7%) personality disorders (2 cluster A and 3 cluster B-C), one anxiolytic dependence disorder and one hypochondriasis. Comparison group had 10 (9.0%) co-morbid diagnoses: 5 anxiety and 5 alcohol use disorders.

Araj√§rvi et al. BMC Psychiatry 2006 6:6   doi:10.1186/1471-244X-6-6

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