|
Allele and genotype distribution of polymorphisms spanning the FKBP5 locus |
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| Controls |
Cases |
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|
|
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| Allele |
Genotype |
Allele |
Genotype |
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|
|
||||||||||||||
| 1 (%) |
2 (%) |
11 |
12 |
22 |
HWE |
1 (%) |
2 (%) |
P-value+ |
11 |
12 |
22 |
HWE |
P-value* |
|
|
|
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| rs4713916 A/G |
110 (29.3) |
266 (70.7) |
18 |
74 |
96 |
0.50 |
160 (32.3) |
336 (67.7) |
0.38 |
19 |
122 |
107 |
0.048 |
0.12 |
| rs1360780 C/T |
262 (69.7) |
114 (30.3) |
94 |
74 |
20 |
0.35 |
338 (68.2) |
158 (31.8) |
0.66 |
114 |
110 |
24 |
0.73 |
0.86 |
| rs3800373 T/G |
275 (73.1) |
101 (26.9) |
102 |
71 |
15 |
0.60 |
344 (69.4) |
152 (30.6) |
0.23 |
115 |
114 |
19 |
0.20 |
0.87 |
|
HWE: P-value of Weir's test for Hardy-Weinberg Equilibrium +: P-value of Fisher's exact test for comparison of allele frequencies between cases and controls *: P-value of Armitage's trend test for comparison of genotype frequencies between cases and controls | ||||||||||||||
Gawlik et al. BMC Psychiatry 2006 6:52 doi:10.1186/1471-244X-6-52 |
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