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Open Access Open Badges Case report

Toxoplasma seropositivity and depression: a case report

Nilamadhab Kar1* and Baikunthanath Misra2

Author Affiliations

1 Wolverhampton Primary Care Trust, Corner House Resource Center, 300 Dunstall Road, Wolverhampton, WV6 0NZ, United Kingdom

2 SCB Medical College, Cuttack, Orissa; India

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BMC Psychiatry 2004, 4:1  doi:10.1186/1471-244X-4-1

Published: 5 February 2004



The association between toxoplasmosis and psychiatric disorders has been reported in a few anecdotal reports.

Case Presentation

A case of depression with toxoplasma seropositivity is presented. The patient with depression showed poor response to antidepressants, for which he was investigated and was found positive on the serological test for the toxoplasma. The response to antidepressant treatment improved only after adequate treatment for toxoplasma.


The case suggests a probable association between toxoplasmosis and depression.