Table 2

Patients’ clinical characteristics and HRQoL at enrolment (N = 637)
Description Values Non naïve (N = 574) Naïve (N = 63) p-value
Diagnosis:
Schizophrenia, n (%) 549 (86.2) 510 (88.9) 39 (61.9) <0.0001*
Schizophreniform disorder, n (%) 88 (13.8) 64 (11.1) 24 (38.1)
Type of schizophrenia:
Catatonic, n (%) 7 (1.3) 7 (1.4) 0 0.661**
Disorganized, n (%) 56 (8.8) 51 (10.0) 5 (12.8)
Paranoid, n (%) 372 (67.8) 345 (67.6) 27 (69.2)
Undifferentiated, n (%) 88 (16.0) 81 (15.9) 7 (17.9)
Residual, n (%) 26 (4.1) 26 (5.1) 0
Duration of illness(years):
Mean (SD) 3.7 (3.0) 4.0 (3.0) 1.2 (2.5) <0.0001
Diagnosis:
<1 year before, n (%) 175 (27.5) 128 (22.3) 48 (76.2) <0.0001*
1–5.99 years before, n (%) 284 (44.6) 273 (47.6) 9 (14.3)
6–10 years before, n (%) 178 (27.9) 173 (30.1) 6 (9.5)
Age at onset of psychotic symptoms(years):
Mean (SD) 24.2 (5.5) 24.1 (5.5) 24.6 (5.9) 0.576
Age at first antipsychotic treatment(years):
Mean (SD) 25.5 (5.4) 25.5 (5.3) 26.1 (6.0) 0.370
Age at first hospitalization(years):
Mean (SD) 26.2 (5.4) 26.2 (5.4) 25.5 (5.8) 0.589
PANSS score
Positive subscale, Mean (SD) 17.3 (7.4) 16.9 (7.2) 21.6 (7.9) <0.0001
Negative subscale, Mean (SD) 23.7 (8.5) 23.5 (8.5) 25.7 (8.3) 0.050
General subscale, Mean (SD) 45.6 (14.6) 44.8 (14.6) 52.7 (13.5) <0.0001
Total, Mean (SD) 86.6 (27.4) 85.2 (27.1) 100.0 (26.2) <0.0001
GAF score:
Mean (SD) 54.1 (13.8) 54.6 (13.9) 49.6 (12.6) 0.007
CGI-S score:
Mean (SD) 4.3 (2.2) 4.3 (1.1) 4.6 (0.9) 0.011
EQ-5D VAS
Mean (SD) 63.5 (17.9) 63.5 (17.9) 63.5 (18.2) 0.991
EQ-5D utility score
Mean (SD) 0.71 (0.3) 0.70 (0.3) 0.72 (0.3) 0.656
SF-36 PCS
Mean (SD) 47.5 (9.3) 47.5 (9.4) 47.4 (9.2) 0.928
SF-36 MCS
Mean (SD) 39.0 (9.6) 39.3 (9.5) 36.6 (10.4) 0.049

* A Chi-square test was applied.

** A Fisher’s exact test was applied.

‡ An independent sample Student’s t-test was applied.

Cortesi et al.

Cortesi et al. BMC Psychiatry 2013 13:98   doi:10.1186/1471-244X-13-98

Open Data