Table 4

Secondary outcome measures: comparing means between the intervention and usual care groups at 15 and 33 weeks post-randomisation
15 weeks post-randomisation 33 weeks post-randomisation (in the postnatal period)
Intervention UC Adjusted difference in means(1) (95% CI) p value Intervention UC Adjusted difference in means (1) (95% CI) p value
n Mean (sd) n Mean (sd) n Mean (sd) n Mean (sd)
CIS-R Scores 16 12.4 (9.2) 13 22.3 (11.1) −10.0 (−16.9 to −2.9) p= 0.007 16 9.8 (8.8) 11 22.4 (11.9) −12.6 (−21.1 to −4.2) p= 0.005
EPDS 16 7.9 (4.7) 13 13.8 (7.5) −5.9 (−10.3 to −1.5) p= 0.01 16 7.1 (4.8) 11 13.7 (6.2) −6.8 (−11.3 to −2.2) p= 0.005
PHQ-9 16 6.2 (4.2) 13 11.8 (7.8) −5.6 (−9.9 to −1.3) p= 0.01 16 6.2 (4.3) 11 10.7 (5.8) −4.7 (−8.8 to −0.6) p= 0.03
Physical component of SF12 score* 16 34.5 (7.8) 13 38.5 (5.8) −4.4 (−9.5 to 0.7) p= 0.09 15 39.8 (6.9) 11 44.9 (12.1) −7.5 (−15.3 to 0.3) p= 0.06
Mental component of SF12 score* 16 52.1 (6.4) 13 42.9 (8.9) 10.2 (4.4 to 16.0) p= 0.001 15 49.2 (4.6) 11 42.8 (11.0) 7.5 (0.9 to 14.0) p= 0.03
Metacognitive awareness questionnaire** 16 44.7 (6.2) 12 41.5 (8.1) 5.1 (−0.3 to 10.5) p= 0.06 15 42 (5.8) 10 39.7 (9.7) 5.0 (−0.5 to 10.4) p= 0.07
EQ-5D* 16 0.78 (0.16) 13 0.72 (0.17) 0.06 (−0.05 to 0.18) p= 0.26 15 0.90 (0.13) 11 0.78 (0.11) 0.13 (0.03 to 0.22) p= 0.01
Prenatal Attachment Inventory 16 60.4 (3.0) 10 47.2 (3.3) 2.6 (2.69 to 22.38) p= 0.01 - - - - -

(1) adjusted for CIS-R score at baseline, age (< or ≥ 18) depression severity (mild, moderate or severe), current symptom duration (< or ≥ 3 months) and history of depression (yes, no).

*High scores reflect better quality of life.

** Higher scores reflect greater cognitive awareness.

Burns et al.

Burns et al. BMC Psychiatry 2013 13:33   doi:10.1186/1471-244X-13-33

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