Table 3 |
||||||||||
| Simple linear regression analyses results of the association between cognition and plasma BDNF levels, pharmacological treatment, IQ, negative symptoms or drug use in the first episode patient group at 6 months after first hospitalisation | ||||||||||
| Similarities | Digit-symbol coding | Logical memory learning curve | Verbal paired associates I learning curve | Verbal paired associates II | ||||||
| r2 | ß (P) | r2 | ß (P) | r2 | ß (P) | r2 | ß (P) | r2 | ß (P) | |
| BDNF plasma levels | 0.194 | 0.468 | 0.130 | 0.397 | 0.291 | 0.559 | 0.140 | 0.409 | 0.118 | 0.382 |
| (0.006) | (0.024) | (0.001) | (0.018) | (0.028) | ||||||
| Pharmacological treatment | −0.027 | 0.025 | −0.025 | −0.056 | 0.011 | 0.193 | −0.002 | −0.157 | 0.002 | −0.117 |
| (0.883) | (0.743) | (0.245) | (0.346) | (0.305) | ||||||
| Wechsler Vocabulary (IQ) | 0.432 | 0.669 | 0.262 | 0.531 | −0.028 | −0.015 | 0.007 | 0.183 | 0.224 | 0.495 |
| (0.000) | (0.001) | (0.928) | (0.270) | (0.002) | ||||||
| Negative symptoms (PANSS N) | 0.257 | −0.530 | 0.081 | −0.335 | −0.033 | −0.014 | 0.038 | −0.264 | 0.052 | −0.288 |
| (0.002) | (0.066) | (0.939) | (0.145) | (0.110) | ||||||
| Tobacco use | 0.034 | 0.246 | 0.080 | 0.325 | 0.074 | 0.315 | −0.011 | 0.127 | 1.046 | 0.120 |
| (0.136) | (0.050) | (0.054) | (0.449) | (0.302) | ||||||
| Alcohol use | −0.020 | 0.111 | −0.020 | −1.112 | 0.001 | 0.179 | 0.053 | 0.287 | −0.017 | 0.120 |
| (0.538) | (0.541) | (0.320) | (0.105) | (0.505) | ||||||
| Cannabis use | −0.021 | −0.102 | −0.017 | −0.121 | −0.027 | 0.067 | 0.001 | 0.178 | −0.027 | 0.064 |
| (0.568) | (0.503) | (0.706) | (0.314) | (0.719) | ||||||
| Other drugs use | 0.025 | 0.083 | 0.059 | −0.299 | −0.018 | 0.117 | −0.013 | 0.137 | −0.032 | −0.002 |
| (0.646) | (0.097) | (0.518) | (0.448) | (0.993) | ||||||
r2: Adjusted R-square; ß: Standardized correlation coefficient.
de Azua et al. BMC Psychiatry 2013 13:27 doi:10.1186/1471-244X-13-27