Table 4

Correlations between demographic and illness characteristics and neurocognitive performance for the total sample of 51 inpatients with therapy-resistant BD depression
Neurocognitive domain Demographic characteristics Course of illness Current symptoms
Gender (male) Age Education Premorbid IQ BD I Duration of illness Number of hospitalizations due to depresssive episodes History of psychotic symptoms Number of psychotic episodes Comorbid substance abuse Comorbid anxiety MADRS PANSS pos GAF-S
  Test (NART)
Speed of Processing -0.09 -0.21 0.25 0.20 -0.25 -0.12 -0.02 -0.14 -0.10 0.09 0.02 0.05 -0.01 -0.05
  BACS–Symbol Coding -0.19 -0.29* 0.28 0.27 -0.06 -0.27 -0.14 -0.04 0.01 0.08 0.17 -0.06 -0.15 0.06
  Fluency -0.09 -0.11 0.20 0.06 -0.35* 0.10 0.22 -0.20 -0.24 0.01 0.05 -0.01 -0.05 0.17
  TMT-A -0.02 -0.19 0.23 0.14 -0.22 -0.15 -0.11 -0.09 -0.11 -0.01 -0.09 0.11 0.09 -0.22
Attention/Vigilance -0.20 -0.46** 0.14 0.00 -0.11 -0.43** -0.29 -0.08 -0.10 0.23 0.20 -0.19 -0.06 -0.10
  CPT
Working memory -0.17 -0.43** 0.36** 0.16 -0.13 -0.27 -0.01 -0.07 -0.07 0.04 0.19 0.01 -0.20 0.05
  Spatial Span -0.10 -0.42** 0.27 0.13 -0.12 -0.21 0.09 0.07 0.08 0.12 0.32 0.10 -0.20 0.00
  Letter-Number Span -0.17 -0.38** 0.37** 0.16 -0.11 -0.31* -0.10 -0.20 -0.20 -0.05 0.05 -0.05 -0.15 0.06
Verbal learning -0.04 -0.37** 0.32* 0.36* -0.14 -0.25 -0.05 -0.20 -0.14 0.05 0.01 0.00 -0.25 0.02
  HVLT-R
Visual learning -0.09 -0.28 0.34 0.16 -0.21 -0.14 0.17 -0.17 -0.12 0.12 0.23 -0.04 -0.14 0.03
  BVMT-R
Reasoning -0.21 -0.19 0.22 0.04 0.04 -0.06 -0.13 0.10 0.08 0.18 0.21 0.07 0.02 -0.04
  Mazes
Mean Composite score -0.18 -0.40** 0.36** 0.22 -0.19 -0.26 -0.07 -0.13 -0.12 0.10 0.15 -0.02 -0.13 -0.04
IQ-decline -0.21 0.17 -0.41** -0.17 0.43** -0.05 0.17 0.40** 0.41* -0.17 -0.01 0.05 0.26 -0.17
  NART-WASI

Spearman’s rho is reported. *p < 0.05; **p < 0.01.

Kessler et al.

Kessler et al. BMC Psychiatry 2013 13:105   doi:10.1186/1471-244X-13-105

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