Table 5

Linear and quadratic correlations of neurocognitive executive functioning to patient anterior insula GMV
Linear correlation Quadratic correlation
Neurocognitive performance Left anterior insula Right anterior insula Left anterior insula Right anterior insula
Set Shifting (IED Total error) ρ(109) = .32** ρ(109) = .13 r(106) = .31** r(106) = .22
Working Memory (SSP) ρ(107) = .08 ρ(107) = −.00 r(104) = .20 r(104) = .16
Mental Flexibility (TMT-B) ρ(114) = −.04 ρ(114) = .04 r(111) = .02 r(111) = .10
Sustained Attention (RVP-A) r(106) = −.08 r(106) = −.05 r(103) = .13 r(103) = .05
Verbal Fluency (COWAT) r(112) = .10 r(112) = .09 r(109) = .10 r(109) = .14

Spearman’s ρ (non-normal score distribution) or Pearson’s r (normal score distribution) correlation analysis explored the linear relationship between the left or right anterior insula GMV (corrected for ICV) against z-scores of neuropsychological assessments of executive function (n = 133), controlling for age. Curve estimation regression explored the quadratic correlation between the same regions of interest and neuropsychological assessments of executive function. **p < .01 (2-tailed).

Hatton et al.

Hatton et al. BMC Psychiatry 2012 12:45   doi:10.1186/1471-244X-12-45

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