Table 2

Frequency of prescriptions of single psychotropic substances
% 1994 - 1997 1998 – 2001 2002 – 2005 2006 - 2009 Overall
N 248 454 711 832 2246
Lithium 2.4 + 42.3 2.9 + 33.5 1.8 + 28.7 1.2 + 33.1 1.9 + 32.8
SSRI overall 2.4 + 15.3 3.5 + 22.4 2.4 + 29 2.0 + 28.6 2.5 + 26.0
Valproic acid 0.4 + 4.8 1.8 + 19.8 1.5 + 28.4 1.3 + 24.4 1.4 + 22.8
Mirtazapine 3.2 2.6 + 12.1 2.1 + 20.7 2.0 + 18.8 2.0 + 16.3
Venlafaxine 2.0 + 4.4 1.1 + 10.4 1.3 + 21.5 1.1 + 18.3 1.2 + 16.2
Quetiapine 0.7 0.3 + 12.7 1.4 + 28.1 0.6 + 14.6
Lamotrigine 0.7 + 2.9 0.1 + 17.7 0.4 + 22.2 0.3 + 14.4
Olanzapine 0.4 0.9 + 9.5 0.7 + 18 1.1 + 13.6 0.8 + 12.7
Carbamazepine 2.0 + 21 1.8 + 18.7 0.4 + 10.4 0.2 + 5.5 0.8 + 11.4
Escitalopram 0.7 + 10.1 1.1 + 14.4 0.6 + 8.5
Citalopram 0.8 + 4.8 1.3 + 8.1 0.8 + 9.8 0.2 + 7 0.7 + 7.9
Risperidone 1.6 0.2 + 5.9 0.1 + 7.3 0.2 + 7.6 0.2 + 6.5
Sertraline 0.4 0.9 + 6.4 0.4 + 5.1 0.5 + 4.0 0.5 + 4.4
Paroxetine 0.8 + 8.5 1.3 + 5.3 0.1 + 2.5 2.4 0.4 + 3.7
Perazine 0.8 + 5.6 0.4 + 5.3 3.1 1.3 0.2 + 3.2
Reboxetine 1.1 + 2.9 0.1 + 4.2 0.2 + 3.0 0.4 + 3.0
Haloperidol 0.8 + 11.3 0.4 + 4.0 1.5 0.7 + 1.3 0.4 + 3.0
Duloxetine 0.1 + 1.5 0.1 + 6.6 0.1 + 2.9
Melperone 2.0 0.2 + 3.3 0.4 + 3.7 2.4 0.2 + 2.9
Promethazine 0.8 + 5.6 0.2 + 3.1 0.1 + 1.4 0.5 + 1.7 0.4 + 2.3
Aripiprazole 1.5 0.1 + 4.7 2.0
Clozapine 3.2 0.2 + 2.2 0.3 + 1.7 0.1 + 1.8 0.2 + 2.0
Fluoxetine 0.8 + 1.6 2.6 0.4 + 1.5 0.2 + 0.8 0.3 + 1.5

Table 2: Monotherapy (small numbers) and combination therapy (fat numbers) in percent (%) of all patients per time period. The substances are listed according to their frequency of prescription, with the most often prescribed substance listed first. Substances with overall prescription rates below 1.5% are not presented. Year of licensing in the respective countries: lamotrigine: epilepsy 1994, long term bipolar depression 2003; olanzapine: schizophrenia 1996, long term mania 2003; quetiapine: schizophrenia 2000, mania 2004, bipolar depression 2009.

Haeberle et al.

Haeberle et al. BMC Psychiatry 2012 12:153   doi:10.1186/1471-244X-12-153

Open Data