Table 1

Demographic, clinical, and polysomnographic data
MDD HC p MDD Females HC Females p MDD Males HC Males p
(N= 30) (N= 30) (N= 19) (N= 19) (N= 11) (N= 11)
Age (years) 26.0 (9.1) 25.4 (8.5) .793 23.4 (5.6) 23.1 (6.2) .891 30.6 (12.1) 29.4 (10.7) .811
HRSD-17 18.6 (2.7) -- 19.0 (3.0) -- 17.9 (1.6) --
TST (min.) 377.8 (66.3) 412.7 (47.5) .023 390.5 (54.0) 419.6 (49.8) .093 356.0 (81.7) 400.8 (42.9) .122
WASO (min.) 43.3 (30.2) 30.2 (20.7) .055 38.1 (26.4) 30.7 (20.6) .345 52.4 (35.4) 29.4 (21.8) .082
AI (#/hr.) 10.6 (5.6) 7.9 (4.3) .043 9.4 (5.5) 8.2 (3.8) .424 12.6 (5.5) 7.4 (5.3) .036
SE (%) 86.5 (7.9) 89.6 (7.4) .132 88.7 (7.1) 89.2 (8.6) .846 82.8 (8.1) 90.1 (4.9) .018
SOL (min.) 15.5 (16.5) 18.6 (24.3) .566 11.6 (10.5) 20.6 (28.0) .199 22.1 (22.7) 15.1 (16.7) .414
N1 (%) 8.1 (5.3) 7.9 (4.7) .926 7.5 (5.5) 7.7 (5.0) .897 9.0 (5.0) 8.3 (4.2) .724
N2 (%) 57.7 (8.1) 60.4 (6.1) .151 56.6 (8.6) 60.4 (5.2) .111 59.5 (7.2) 60.4 (7.8) .788
N3 (%) 16.8 (9.2) 14.8 (7.1) .348 20.0 (7.6) 15.9 (6.3) .075 11.2 (9.3) 13.0 (8.2) .651
REM (%) 18.1 (6.6) 16.9 (5.0) .448 15.9 (6.5) 16.0 (5.2) .923 22.3 (4.8) 18.4 (4.5) .071
REML (min.) 131.2 (77.4) 122.2 (69.7) .641 158.1 (78.4) 131.1 (71.2) .275 80.1 (43.7) 106.7 (67.4) .302
SWA (μV2/Hz) 22.7 (13.1) 17.3 (6.8) .054 28.8 (12.4) 19.3 (6.8) .006 12.1 (5.4) 13.9 (5.3) .442

MDD, major depressive disorder; HC, healthy control; HRSD-17, Hamilton Rating Scale for Depression (17-item); TST, total sleep time; WASO, wake after sleep onset; AI, arousal index; SE, sleep efficiency (TST/time in bed); SOL, sleep onset latency; N1/2/3, NREM stage 1/2/3 (% of TST); REM, stage REM (% of TST); REML, REM latency (time from sleep onset to first REM sleep epoch); SWA, global slow wave activity (EEG power in 1 – 4.5 Hz range average 185 channels);

Values are displayed as mean (standard deviation).

*2-tailed, independent samples t-tests.

Plante et al.

Plante et al. BMC Psychiatry 2012 12:146   doi:10.1186/1471-244X-12-146

Open Data