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Epidemiologic Studies of SSPE |
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| Country and years (reference) |
Study method |
Incidence and immunization status of population |
SSPE cases per Measles cases in general population in relevant time period (cases of SSPE/million cases of measles) |
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| State of California, USA, 1998–2003 [41] |
Passive surveillance. |
5 cases over 5.5 years. Active immunization. |
4 cases related to a 2 year epidemic of 16,400 cases of measles in California. (243 cases/million) |
| Bulagria 1978–2002 [42],[43] |
University hospital sample. |
40 cases over 25 years. No population figures given. Active immunization. |
Not available. |
| South China 1988–2002 [44] |
Physician survey and hospital record diagnostic code search. |
5.5/million children. Active immunization. |
At least 6 cases related to a epidemic of 4140 cases in one year. (1449 cases/million) |
| England and Wales 1990–2002 [45] |
Passive surveillance. |
47 cases (not all pediatric). No incidence figures given. Active immunization. |
1 case per 25,000 measles infections. 1 case per 5,500 if measles infection in first year. (40–200 cases/million) |
| Japan 1977–1999 [46] |
Unclear from abstract. |
0.58/million population |
Not available. |
| Papua New Guinea 1997–1999 [47] |
Single hospital sample. |
98/million child population. Active immunization but poor coverage. |
Not available. |
| Australia 1995–1998 [48] |
Active surveillance. |
0.02/100,000 children per year |
Not available. |
| Brazil 1990–1996 [49] |
Survey of child neurologists with 84% response rate. |
48 cases over 7 years |
Not available. |
| USA 1980 [1] |
Passive surveillance. |
0.06/million population under 20 years |
8.5 cases of SSPE/million cases of measles infection for 1960–1974. |
Campbell et al. BMC Pediatrics 2005 5:47 doi:10.1186/1471-2431-5-47 |
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