Table 4

Univariate analysis: Specific clinical signs at 3 – 5 hours as predictors of abnormal 6-hour aEEG
Predictor n Abnormal aEEG n (%) Sensitivity (95%CI) Specificity (95%CI) LR + (95%CI) LR - (95%CI) LR Test (Odds ratio) (95%CI)
Decreased LOC Yes 31 24 (77) 67% 71% 2.29 0.47 4.86
No 29 12 (41) (49 – 81) (49 – 87) (1.18 – 4.44) (0.28 – 0.8) (1.61 – 14.61)
Seizures visible Yes 20 17 (85) 47% 88% 3.78 0.6 6.26
No 40 19 (48) (30 – 65) (68 – 97) (1.24 – 11.5) (0.43 – 0.85) (1.67 – 23)
Hypotonia Yes 14 12 (86) 33% 92% 3.38 a 0.74 a 4.59 a
No 46 24 (52) (19 – 51) (73 – 99) (0.96 – 11.9) (0.56 – 0.96) (1.05 – 20.04)
Stretch reflexes abnormal Yes 40 31(78) 86% 63% 2.3 0.22 10.33
No 20 5 (25) (71 – 95) (41 – 81) (1.35 – 3.91) (0.09 – 0.53) (3.02 – 35.2)
Primitive reflexes abnormal Yes 60 36 (100) 100% 0% 1.01 a 0.68 a 1.49 a
No 0 0 (0) (90 – 100) (0 – 14) (0.94 – 1.08) (0.01 – 32.95) (0.03 – 77.62)

a: When zero count cells are present, LR is estimated using a substitution formula: 0.5 is added to all cell frequencies before calculation.

LOC: Level of consciousness, LR:Likelihood ratio, aEEG: amplitude-integrated EEG.

Horn et al.

Horn et al. BMC Pediatrics 2013 13:52   doi:10.1186/1471-2431-13-52

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