Table 3

Prediction of abnormal 6-hour aEEG with different encephalopathy assessment methods at 3 – 5 hours
Encephalopathy assessment n Abnormal aEEG n (%) Sensitivity (95%CI) Specificity (95%CI) LR + (95%CI) LR - (95%CI) LR Test (Odds ratio) (95%CI)
Moderate-severe encephalopathy Yes 42 35 (83) 97% 71% 3.2 a 0.06 a 55.22 a
No 18 1 (6) (86 – 100) (49 – 87) (1.75 – 5.84) (0.01 – 0.28) (8.73 – 349.15)
Thompson score ≥ 7 Yes 44 36 (82) 100% 67% 2.9 a 0.02 a 141.71 a
No 16 0 (0) (90 – 100) (45 – 84) (1.7 – 5) (0 – 0.33) (7.71 – 2603.42)

LR: Likelihood ratio, aEEG: amplitude-integrated EEG,

a : When zero count cells are present, LR is estimated using a substitution formula: 0.5 is added to all cell frequencies before calculation.

Horn et al.

Horn et al. BMC Pediatrics 2013 13:52   doi:10.1186/1471-2431-13-52

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