Table 3 |
|||
| Differences between survivors without significant BPD and deceased or surviving infants with significant BPD | |||
| SWsBPD | Deceased/Significant BPD | p-value* | |
| (n = 299) | (n = 116) | ||
| Year of birth | 0.032 | ||
| - 1997–2000 | 38 (58.5%) | 27 (41.5%) | |
| - 2001–2005 | 132 (74.2%) | 46 (25.8%) | |
| - 2006–2009 | 129 (75.0%) | 43 (25.0%) | |
| Gestational age (w) | 27.6 (26.1-29.4) | 25.4 (24.4-27.0) | <0.001 |
| Birth weight (g) | 850 (750–935) | 680 (589–780) | <0.001 |
| IUGR | 112 (38.5%) | 37 (34.9%) | 0.515 |
| Multiple gestation | 102 (34.1%) | 48 (41.4%) | 0.167 |
| Male gender | 135 (45.2%) | 63 (54.3%) | 0.094 |
| Chorioamnionitis | 48 (16.1%) | 33 (28.4%) | 0.004 |
| Antibiotics (mother) | 167 (59.6%) | 78 (69.6%) | 0.065 |
| Prenatal steroids | 277 (95.2%) | 97 (84.3%) | <0.001 |
| Cesarean section | 213 (72.0%) | 53 (45.7%) | <0.001 |
| Apgar at 1 minute ≤3 | 29 (9.7%) | 37 (32.5%) | <0.001 |
| Apgar at 5 minutes ≤6 | 29 (9.7%) | 32 (28.3%) | <0.001 |
| Umbilical artery pH | 7.26 (7.17-7.31) | 7.29 (7.19-7.32) | 0.165 |
| Resuscitation | <0.001 | ||
| - Not performed | 67 (22.4%) | 6 (5.2%) | |
| - Mask/IPPV + PEEP | 121 (40.5%) | 20 (17.2%) | |
| - ET intubation | 102 (34.1%) | 79 (68.1%) | |
| - ET Intubation + | |||
| chest compression + | |||
| epinephrine | 9 (3.0%) | 11 (9.5%) | |
| CRIB | 4 (1–6) | 9 (7–13) | <0.001 |
| RDS | 146 (48.8%) | 92 (79.3%) | <0.001 |
| Mechanical ventilation | 184 (61.5%) | 116 (100%) | <0.001 |
| Sepsis | 124 (41.5%) | 54 (46.6%) | 0.349 |
| NEC | 17 (5.7%) | 13 (11.2%) | 0.052 |
| IVH | 52 (17.4%) | 45 (38.8%) | <0.001 |
| - Grades III/IV | 11 (3.7%) | 34 (29.3%) | <0.001 |
| PVLM | 6 (3.1%) | 4 (4.5%) | 0.536 |
| PDA | 105 (35.1%) | 43 (37.1%) | 0.710 |
| - Surgical closure | 25 (8.4%) | 6 (5.2%) | 0.268 |
| Severe arterial | |||
| hypotension | 10 (3.4%) | 30 (26.1%) | <0.001 |
CRIB: clinical risk index for babies; IUGR: intrauterine growth restriction; ET: endotracheal; RDS: respiratory distress syndrome; NEC: necrotizing enterocolitis; IVH: peri-intraventricular hemorrhage; PEEP: positive end expiratory pressure; PVLM: periventricular leukomalacia; PDA: patent ductus arteriosus; SWsBPD: survival without significant BPD.
Median (IQR: 25th-75th percentile), number (%).
* Mann–Whitney U or chi-square test.
Botet et al. BMC Pediatrics 2012 12:63 doi:10.1186/1471-2431-12-63
