Ravi K Lingineni, Swati Biswas*, Naveed Ahmad, Bradford E Jackson, Sejong Bae and Karan P Singh
Corresponding author: Swati Biswas firstname.lastname@example.org
BMC Pediatrics 2012, 12:50 doi:10.1186/1471-2431-12-50
(2012-06-28 16:03) University of North Texas Health Science Center
Thank you very much for your interest in our work and bringing up this important issue.
The data that we used for this study (NCSH) didn't have any information on prenatal
exposures so even though we are aware of importance of those exposure variables, we
couldn't use them in our analyses. The cross-sectional nature of our data has been
mentioned as a limitation in the paper.
(2012-06-11 16:33) FASlink Fetal Alcohol Disorders Society
Prenatal exposure to alcohol is a major factor in ADHD, with ADHD co-occurring more
than 90% of the time with Fetal Alcohol Spectrum Disorders. I am concerned that prenatal
alcohol exposure was not a factor considered in this study. In Canada, 37% of babies
have been exposed to binge drinking of 5 or more drinks per occasion on multiple occasions
during the pregnancy. Another 42% have been exposed to 1 to 4 drinks of alcohol multiple
times during the pregnancy. Only 21% of females giving birth do not drink alcohol.
There is no known safe level of alcohol exposure during pregnancy. The most vulnerable
time is the first trimester. The pregnancy may not have been confirmed for three or
more months. More than half of the pregnancies are unplanned. Alcohol crosses the
placental barrier and is a toxin, teratogen, and mutagen, affecting more than 1000
gene and cell processes including proliferation, transport and communications. More
than 20% of Canadian Children are receiving Special Education, more than half of those
for conditions of types known to be caused by prenatal alcohol exposure. Failure to
consider prenatal alcohol exposure as a risk factor for ADHD is a serious omission
in this study. Please see: http://www.faslink.org/Probabilityofprenatalalcoholexposure.pdf
BioMed Central Ltd unless otherwise stated. Part of Springer Science+Business Media.