Table 9

Power to evaluate secondary outcomes
Secondary outcome Total births
Birthweight (difference of 100 gm)* 928
Birthweight (difference of 200 gm)* 234
Gestational age (difference of 2 days* 2484
Gestational age (difference of 4 days* 622
Pre-eclampsia-Change by 40% from 10% baseline rate 1540
Pre-eclampsia-Change by 50% from 10% baseline rate 948
Severity (50% change from cleft lip with palate to cleft lip only in affected cases with 25% overall cleft prevention) 680
Miscarriage (30% change from 15% baseline rate) 1629
Miscarriage (50% change from 15% baseline rate) 562
* Assumes SD of 543 grams (birthweight) and 17.8 days (gestational age) as estimated in our studies in these populations.

Wehby et al.

Wehby et al. BMC Pediatrics 2012 12:184   doi:10.1186/1471-2431-12-184

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