Table 3

Laboratory measures
Laboratory measure Timing Aim Performed by
Complete blood count At baseline, every 12 months post initiation of supplementation, and at pregnancy confirmation. Anemia Laboratory of study clinic
Pregnancy test Whenever menstrual delay of 14 days or more is detected Pregnancy Laboratory of study clinic or an outside affiliated laboratory
Folate analysis At baseline, every 12 months post initiation of supplementation, and at pregnancy confirmation. Measure serum/red cell folate concentration Laboratory of study clinic or an outside affiliated laboratory
Vitamin B12 analysis At baseline and every 12 months thereafter Detect pernicious anemia Laboratory of study clinic or an outside affiliated laboratory

Wehby et al.

Wehby et al. BMC Pediatrics 2012 12:184   doi:10.1186/1471-2431-12-184

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